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Anti-CLCN4 / CLC-4 Antibody (aa663-689) LS-C100107

Ordering

Wt. Vol. Conc. Price
- 400 µl - $305
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular CLCN4 / CLC-4 Antibodies

Anti-CLCN4 / CLC-4 Antibody (C-Terminus, AP) LS-C276294
Rabbit Polyclonal (IgG) to Human CLCN4 / CLC-4
Human
ICC, Immunofluorescence, Western blot, ELISA
AP Conjugated
Anti-CLCN4 / CLC-4 Antibody (C-Terminus, Biotin) LS-C276297
Rabbit Polyclonal (IgG) to Human CLCN4 / CLC-4
Human
ICC, Immunofluorescence, Western blot, ELISA
Biotin Conjugated
Anti-CLCN4 / CLC-4 Antibody (C-Terminus, Azide-free, HRP) LS-C276298
Rabbit Polyclonal (IgG) to Human CLCN4 / CLC-4
Human
ICC, Immunofluorescence, Western blot, ELISA
HRP Conjugated, Azide-free

100% Guaranteed 100% Guaranteed
Rabbit Polyclonal to Human CLCN4 / CLC-4
Human
IHC, Immunofluorescence, Western blot
Unconjugated

Details

Human CLCN4 / CLC-4
Rabbit
Human (tested or 100% immunogen sequence identity)
Polyclonal
Unconjugated
Ammonium sulfate precipitation
Unmodified

Applications

  • IHC (1:10 - 1:50)
  • Immunofluorescence (1:10 - 1:50)
  • Western blot (1:1000)

Specificity and Use

CLCN4 / CLC-4 antibody was raised against kLH-conjugated synthetic peptide between amino acids 663-689 from C-terminal region of human CLC4.
LS-E8210 - Lyophilized - 100 µg - $145.00
aa663-689

Packaging

PBS, 0.09% sodium azide
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
For research use only.

About CLCN4 / CLC-4

P51793 NM_001830 NP_001821.2

CLCN4 Antibody, ClC-4 Antibody, Chloride channel 4 Antibody, Chloride channel protein 4 Antibody, Chloride transporter ClC-4 Antibody, ClC-4A Antibody, CLC4 Antibody

The CLCN family of voltage-dependent chloride channel genes comprises nine members (CLCN1-7, Ka and Kb) which demonstrate quite diverse functional characteristics while sharing significant sequence homology. Chloride channel 4 has an evolutionary conserved CpG island and is conserved in both mouse and hamster. This gene is mapped in close proximity to APXL (Apical protein Xenopus laevis-like) and OA1 (Ocular albinism type I), which are both located on the human X chromosome at band p22.3.

Immunohistochemistry

Immunohistochemistry
Retinae were collected from adult White Leghorn chicken and fixed in the eyecup for two hours in 4% Paraformaldehyde (in PBS). Retinae were then removed from the eyecups and incubated in 30% sucrose (in PBS) overnight. Retinal tissue was embedded and frozen in OCT compound and cut into ~15um sections on a cryotome. Sections were blocked in 5% normal goat serum (in 1%BSA/.1%saponin PBS) for one hour and then incubated at RT with 1:250 (1%BSA/.1% saponin PBS) ClC4 antibody for 1 hour. Sections were then washed in PBS (3X10minutes) and then treated with secondary antibody (1:500 Cy3) for one hour. After another PBS wash series, sections were coverslipped and antibody labeling was visualized at 20X with a Leica upright microscope using a TRITC filter set and Xenon LAMP illumination. (Crousillac et al, 2003)

Immunofluorescence

Immunofluorescence
Immunofluorescence image of cultured chick retinal amacrine (neuronal) cells labeled with CLC4 Antibody. Data courtesy of Emily McMains, Louisiana State University.

Western blot

Western blot
Western blot of chicken brain tissue incubated with CLC4 Antibody. Data courtesy of Emily McMains, Louisiana State University.
 

Requested From: United States
Date Requested: 12/5/2016

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