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After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.
Gene Name: | cholinergic receptor, nicotinic, alpha 1 (muscle) |
Family/Subfamily: | Ion Channel , Nicotinic acetylcholine receptor |
Synonyms: | CHRNA1, Achr-1, AChR-alpha1, ACHRD, CHNRA, ACHRA, FCCMS, SCCMS, CHRNA, CMS2A, NAChR alpha 1 |
Target Sequences: | NM_000079 NP_000070.1 P02708 |
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