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Anti-CFH / Complement Factor H Antibody LS-C11326

Note: This antibody replaces LS-C23338, LS-C23334, LS-C123508

100% Guaranteed 100% Guaranteed
Sheep Polyclonal (IgG) to Human CFH / Complement Factor H
Human, Mouse, Rat, Cat, Dog, Guinea pig, Horse
Immunodiffusion
Unconjugated

Details

Human CFH / Complement Factor H
Sheep
Human, Mouse, Rat, Cat, Dog, Guinea pig, Horse (tested or 100% immunogen sequence identity)
Bovine, Goat, Pig, Rabbit, Chicken
IgG Polyclonal
Sterile filtered

Applications

Immunodiffusion

Specificity and Use

CFH / Complement Factor H antibody was raised against highly purified human Factor H.
Recognizes human Factor H, a cofactor involved in the regulation of the alternative complement pathway. In IEP a single arc is observed against human plasma. Identity has been confirmed by double diffusion against human plasma and a known anti-human Factor H antibody. Deficiency in factor H can lead to diseases such as Hemolytic-uremic syndrome and chronic hypocomplementemic nephropathy. Has been used successfully as a capture reagent for the measurement of murine factor H in mouse serum samples by sandwich ELISA in conjunction withas a detection reagent.

Packaging

Glycine buffered saline., pH 7.4, 0.09% sodium azide, 0.1% EACA, 0.01% benzamidine, 1 mM EDTA.
+4°C or -20°C, Avoid repeated freezing and thawing.
For research use only.

About CFH / Complement Factor H

P08603 NM_000186 NP_000177.2

CFH Antibody, Adrenomedullin binding protein Antibody, AHUS1 Antibody, AMBP1 Antibody, ARMS1 Antibody, ARMD4 Antibody, Beta-1-H-globulin Antibody, Factor H Antibody, Factor H-like 1 Antibody, HF Antibody, HF2 Antibody, H factor 1 Antibody, H factor 2 (complement) Antibody, HUS Antibody, HF1 Antibody, Beta-1H Antibody, CFHL3 Antibody, Complement factor H Antibody, H factor 1 (complement) Antibody

CFH / Complement Factor H is a member of the Regulator of Complement Activation (RCA) gene cluster and encodes a protein with twenty short consensus repeat (SCR) domains. This protein is secreted into the bloodstream and has an essential role in the regulation of complement activation, restricting this innate defense mechanism to microbial infections. Mutations in this gene have been associated with hemolytic-uremic syndrome (HUS) and chronic hypocomplementemic nephropathy.

Requested From: United States
Date Requested: 9/27/2016

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