The Immunohistochemistry Antibody Company
|Human Ceramide Kinase / CERK|
|Human (tested or 100% immunogen sequence identity)|
|Ceramide Kinase / CERK antibody was raised against a synthetic peptide made to an internal portion of the human ceramide kinase protein sequence (between residues 50-150). [Swiss-Prot Q8TCT0] Percent identity by BLAST analysis: Mouse (86%).|
|The applications listed have been tested for the base form of this product. Alternate forms, such as conjugated, azide-free, or ready-to-use, have not been tested.|
|Store at 4°C. Do not freeze.|
|For research use only.|
CERK Antibody, Acylsphingosine kinase Antibody, Ceramide kinase Antibody, DA59H18.2 Antibody, DA59H18.3 Antibody, KIAA1646 Antibody, Lipid kinase 4 Antibody, Lipid kinase LK4 Antibody, HCERK Antibody, LK4 AntibodyCERK, which phosphorylates Cer to produce ceramide 1-phosphate (C1P), was initially described as a Ca2+-stimulated lipid kinase that copurified with brain synaptic vesicles. CERK activity has been reported in HL60 cells, mast cells, and neutrophils. CERK is involved in phagolysosome formation in polymorphonuclear leukocytes and also in liposome fusion. C1P has been reported to have mitogenic effects. More recently, C1P was found to induce arachidonic acid release and prostanoid synthesis.