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Anti-CDK5 Antibody (C-Terminus) LS-C42580

Ordering

Wt. Vol. Conc. Price
- 50 µl - $350
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular CDK5 Antibodies

Anti-CDK5 Antibody LS-C22052
Mouse Monoclonal (IgG2a) to Human CDK5
Human, Mouse, Rat, Drosophila
ICC, Western blot, Immunoprecipitation, ELISA
Unconjugated
Anti-CDK5 Antibody (C-Terminus) IHC-plus™ LS-B353
Rabbit Polyclonal to Human CDK5
Human, Mouse, Rat
IHC - Paraffin, Western blot, Immunoprecipitation, ELISA
Unconjugated
Immunohistochemistry Image

100% Guaranteed 100% Guaranteed
Rabbit Polyclonal (IgG) to Human CDK5
Human, Mouse, Rat
Western blot, Immunoprecipitation, ELISA
Unconjugated

Details

Human CDK5
Rabbit
Human, Mouse, Rat (tested or 100% immunogen sequence identity)
IgG Polyclonal
Unconjugated
Unmodified

Applications

  • Western blot
  • Immunoprecipitation
  • ELISA (1:500 - 1:2000)

Specificity and Use

CDK5 antibody was raised against peptide corresponding to C-terminus of human Cdk5 conjugated to Keyhole Limpet Hemocyanin (KLH). ( C-TERMINAL ).
C-Terminus
Detects human cyclin dependent kinase 5 (Cdk5), a proline-directed serine/threonine protein kinase that unlike most Cdks does not function in cell cycle control, and is not regulated by cyclins. Instead, it requires the association p35 or p39 for its kinase activity, resulting in a master regulator of neuronal functions, with roles in neuronal survival and migration, neurotransmitter release and axon guidance. Cdk5 is ubiquitously expressed, but expression and activity is highest in post mitotic neurons, where p35 and p39 are highly expressed. Deregulation of this kinase is neurotoxic and might contribute to the pathogenesis of Alzheimer's disease and other neurodegenerative disorders.

Packaging

Serum, 0.01% sodium azide.
For research use only.

About CDK5

Q00535 NM_004935 NP_004926.1

CDK5 Antibody, CDKN5 Antibody, Cell division protein kinase 5 Antibody, Crk6 Antibody, Cyclin-dependent kinase 5 Antibody, Protein kinase CDK5 splicing Antibody, PSSALRE Antibody, TPKII catalytic subunit Antibody

Proline-directed serine/threonine-protein kinase essential for neuronal cell cycle arrest and differentiation and may be involved in apoptotic cell death in neuronal diseases by triggering abortive cell cycle re-entry. Interacts with D1 and D3-type G1 cyclins.

Requested From: United States
Date Requested: 12/8/2016

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