Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse Monoclonal [clone DCS-121] (IgG2a) to Human CDC25A
Western blot, Immunoprecipitation
Human (tested or 100% immunogen sequence identity)
IgG2a Monoclonal [DCS-121]
Immunoprecipitation (1 - 10 µg/ml)
Specificity and Use
CDC25A antibody was raised against purified recombinant CDC25A.
Recognizes human Cdc25A, a 65kD protein phosphatase which plays an important role in cell cycle regulation. Cdc25A appears to have a critical role in the regulation of G1/S transition of mammalian cells.
CDC25A, a CDC25 dual specificity protein phosphatase, has been shown to activate the cyclin-dependent kinases at different points of the cell cycle. CDC25A has been shown to affect S phase entry and possibly the initiation of mitosis. CDC25A dephosphorylates cyclin dependent kinases, including Cdk2, Cdk4, as well as non cyclin proteins such as the homeodomain transcription factor cut, the proto-oncogene Raf-1.