Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Human (tested or 100% immunogen sequence identity)
Tissue culture supernatant
IHC - Paraffin
IHC - Frozen (1:75 - 1:150)
Specificity and Use
CD9 antibody was raised against recombinant human CD9.
Recognizes the human CD9 cell surface antigen. CD9 is a 24-27kD glycoprotein which is a member of the tetraspan family, being expressed by B cells, monocytes, platelets and by neurons and glial cells. In melanoma and breast cancer CD9 antigen expression may be linked to a favorable prognosis.
Immunohistochemistry: (frozen)- 1:75-1:150, (paraffin)- 1:20-1:40. Positive control: Human tonsil.
1,000 µl deionized water
Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.
CD9 is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Tetraspanins are cell surface glycoproteins with four transmembrane domains that form multimeric complexes with other cell surface proteins. The encoded protein functions in many cellular processes including differentiation, adhesion, and signal transduction, and expression of this gene plays a critical role in the suppression of cancer cell motility and metastasis.