Duck CD8A / CD8 Alpha

Mouse

Duck (tested or 100% immunogen sequence identity)

Chicken

IgG2b Monoclonal

Du CD8-1

Unconjugated

Protein G purified

Unmodified

293T cells expressing Peking Duck CD8 alpha.

Recognizes Peking duck CD8 alpha (CD8-alpha), shown to be expressed by thymocytes, splenocytes, peripheral lymphoid cells and the vast majority of bursal cells. Since the majority of avian immune studies have been carried out on chickens, relatively little is known about the immune system of ducks, though there is a resemblance between the main lymphoid organs: the spleen, thymus and bursa of Fabricius. At the cellular level, studies have shown that like mammalian T cells, duck lymphocytes are responsive to phytohemagglutinin (PHA). Double-staining with clone Du CD8-1 and duck IgY light chain clone 14A3 (product code MCA2480 ), revealed the presence of a CD8high /14A3- cytotoxic T cell population and a CD8low/14A3+ B cell population in duck spleen and also revealed a high percentage of CD8+/14A3+ cells in duck bursa.

• IHC - Paraffin
• Immunoprecipitation
• Flow Cytometry

Flow Cytometry: Use 10 ul of the suggested working dilution to label 10^6 cells in 100 ul. Method sheets are available on request.

PBS, 0.09% Sodium Azide

Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.

For research use only. Intended for use by laboratory professionals.

This antibody carries the LSBio 100% Guarantee.

Uniprot: P01732 NCBI: NM_001768 NP_001759.3