Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse Monoclonal [clone MRC OX-8] (IgG1) to Rat CD8A / CD8 Alpha
IHC - Paraffin, IHC - Frozen, Flow Cytometry
Rat CD8A / CD8 Alpha
Rat (tested or 100% immunogen sequence identity)
IgG1 Monoclonal [MRC OX-8]
Protein G purified
IHC - Paraffin
IHC - Frozen
Flow Cytometry (0.1 µg/10E6 cells)
Specificity and Use
CD8A / CD8 Alpha antibody was raised against high molecular weight rat thymocyte glycoproteins.
Anti-rat T cytotoxic/suppressor cell monoclonal antibody recognizes a determinant on the majority of thymocytes (90-95%), a subset of peripheral T cells, the majority of NK cells, and the granular intraepithelial leukocytes in the small intestine. The ant.
PBS, 0.02% sodium azide.
Store at 4°C for short term applications. For long term storage, aliquot and store at -20°C.
The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains or as a heterodimer composed of one alpha and one beta chain.