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Anti-CD86 Antibody (clone 24F, FITC) LS-C188423

Ordering

Wt. Vol. Conc. Price
100 µg - 0.1 mg/ml $280
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular CD86 Antibodies

Anti-CD86 Antibody (clone BU63, FITC) LS-C112510
Mouse Monoclonal [clone BU63] (IgG1) to Human CD86
Human
Flow Cytometry
FITC Conjugated
Anti-CD86 Antibody IHC-plus™ LS-B11911
Rabbit Polyclonal (IgG) to Human CD86
Human, Mouse
IHC, IHC - Paraffin, ICC, Immunofluorescence, Western blot, Immunoprecipitation
Unconjugated
Immunohistochemistry Image

100% Guaranteed 100% Guaranteed
Mouse Monoclonal [clone 24F] (IgG1) to Rat CD86
Rat
Flow Cytometry
FITC Conjugated

Details

Rat CD86
Mouse
Rat (tested or 100% immunogen sequence identity)
IgG1 Monoclonal [24F]
Fluorescein
Protein G purified
Unmodified

Applications

Flow Cytometry (1:1 - 1:10)

Specificity and Use

CD86 antibody was raised against hTLV-1 transformed Lewis-S1 cells.
Recognizes rat CD86, otherwise known as B7-2, a type I transmembrane protein and member of the Ig superfamily, which acts as a ligand for both CD28 and CD152 (CTLA-4), and is primarily expressed on antigen presenting cells (APCs) including dendritic cells, and also on germinal centre B cells and macrophages. Like CD80, CD86 is an accessory molecule which functions in the CD28-CD80/CD86 co-stimulatory pathway, vital for T cell activation, crosstalk between T and B cells, and Th2-mediated Ig production. Clone 24F has been shown to block the co-stimulatory activity of rat CD86.
The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

Packaging

PBS, 0.09% sodium azide, 1% BSA
Long term: -20°C; Short term: +4°C; Avoid freeze-thaw cycles. Protect from light.
For research use only.

About CD86

P42081 NM_006889 NP_008820.3

CD86 Antibody, Activation B7-2 antigen Antibody, B7-2 Antibody, B7.2 Antibody, B70 Antibody, CD86 molecule Antibody, CTLA-4 counter-receptor B7.2 Antibody, CD86 antigen Antibody, FUN-1 Antibody, LAB72 Antibody, BU63 Antibody, CD28LG2 Antibody, Ctla-4 counter-receptors b7.2 Antibody

CD86 is a type I membrane protein that is a member of the immunoglobulin superfamily. It is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell.

Flow Cytometry

Flow Cytometry
Flow cytometry of rat splenocytes with Mouse anti-Rat CD86:FITC This image was taken for the unconjugated form of this product. Other forms have not been tested.
 

Requested From: United States
Date Requested: 12/7/2016

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