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Anti-CD71 / Transferrin Receptor Antibody (clone ER-MP21, Biotin) LS-C96384

Ordering

Wt. Vol. Conc. Price
200 µg - - $465
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular CD71 / Transferrin Receptor Antibodies

Anti-CD71 / Transferrin Receptor Antibody (clone OX-26) LS-C43743
Mouse Monoclonal [clone OX-26] (IgG2a) to Rat CD71 / Transferrin Receptor
Rat
IHC - Frozen, Flow Cytometry
Unconjugated
Anti-CD71 / Transferrin Receptor Antibody (aa3-28, clone H68.4) IHC-plus™ LS-B2124
Mouse Monoclonal [clone H68.4] (IgG1) to Human CD71 / Transferrin Receptor
Human, Mouse, Rat, Hamster, Chicken
IHC - Paraffin, ICC, Immunofluorescence, Western blot, Immunoprecipitation, ELISA
Unconjugated
Immunohistochemistry Image
Anti-CD71 / Transferrin Receptor Antibody (clone 1E6) IHC-plus™ LS-B6156
Mouse Monoclonal [clone 1E6] (IgG2b,k) to Human CD71 / Transferrin Receptor
Human
IHC - Paraffin, Western blot, ELISA
Unconjugated
Immunohistochemistry Image

100% Guaranteed 100% Guaranteed
Rat Monoclonal [clone ER-MP21]
Mouse
IHC - Frozen
Biotin Conjugated

Details

CD71 / Transferrin Receptor
Rat
Mouse (tested or 100% immunogen sequence identity)
Monoclonal [ER-MP21]
Biotin
Affinity purified
Unmodified

Applications

IHC - Frozen (1:200)

Specificity and Use

CD71 / Transferrin Receptor antibody was raised against macrophage precursor cells
The antigen is a 200kDa protein (non-reducing conditions) consisting of two identical chains. The recognized epitope of the receptor is not located at the transferrin binding site. Antigen distribution: Differentiation stage-dependent inhibition of macrophage proliferation by ER-MP21 in MCSF-stimulated bone marrow cultures. Macrophage progeny at day 7 in bone marrow cultures, treated in parallel on various days by irradiation (1500 rad 60Co gamma-radiation) or addition of ER-MP21 (30 ug/ml final concentration). Cell numbers were quantified using the MTT assay and expressed relative to untreated controls. Relative growth inhibition calculated from data represented in left figure. For mAbor radiation treated cultures, the number of cell cycles needed to reach the cell number in untreated controls was calculated. Values obtained for irradiated cultures were taken as 100% inhibition controls and values for ER-MP21 - treated cultures were expressed relative to these. Specificity: Mouse: transfer in receptor. Other species: not tested.
The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

Packaging

Lyophilized from PBS pH 7.2, 10mg/ml BSA, 0.1% sodium azide
0.5ml distilled water
Store at 4°C.
For research use only.

About CD71 / Transferrin Receptor

P02786 NM_003234 NP_003225.2

TFRC Antibody, CD71 Antibody, TFR1 Antibody, TRFR Antibody, TFR Antibody, TR Antibody, CD71 antigen Antibody, p90 Antibody, T9 Antibody, Transferrin receptor Antibody, Transferrin receptor protein 1 Antibody

Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system By similarity.

Requested From: United States
Date Requested: 12/9/2016

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