Mouse CD71 / Transferrin Receptor

Rat

Mouse (tested or 100% immunogen sequence identity)

Monoclonal

ER-MP21

Biotin

Affinity purified

Unmodified

Macrophage precursor cells

The antigen is a 200kDa protein (non-reducing conditions) consisting of two identical chains. The recognized epitope of the receptor is not located at the transferrin binding site. Antigen distribution: Differentiation stage-dependent inhibition of macrophage proliferation by ER-MP21 in MCSF-stimulated bone marrow cultures. Macrophage progeny at day 7 in bone marrow cultures, treated in parallel on various days by irradiation (1500 rad 60Co gamma-radiation) or addition of ER-MP21 (30 ug/ml final concentration). Cell numbers were quantified using the MTT assay and expressed relative to untreated controls. Relative growth inhibition calculated from data represented in left figure. For mAbor radiation treated cultures, the number of cell cycles needed to reach the cell number in untreated controls was calculated. Values obtained for irradiated cultures were taken as 100% inhibition controls and values for ER-MP21 - treated cultures were expressed relative to these. Specificity: Mouse: transfer in receptor. Other species: not tested.

• IHC
• IHC - Frozen (1:200)

The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

Lyophilized from PBS pH 7.2, 10mg/ml BSA, 0.1% sodium azide

Reconstitute with 0.5ml distilled H2O.

Store at 4°C.

For research use only. Intended for use by laboratory professionals.

This antibody carries the LSBio 100% Guarantee.

Uniprot: P02786 NCBI: NM_003234 NP_003225.2