LSBio The Immunohistochemistry Antibody Company
Products
  • Antibodies
  • All Antibodies
  • Primary Antibodies
  • Secondary Antibodies
  • IHC-plus Antibodies
  • Isotype Control Antibodies
  • ELISA Kits
  • All Kits
  • Sandwich ELISA Kits
  • Competitive EIA Kits
  • Cell-Based ELISA Kits
  • DNA-Binding ELISA Kits
  • Direct ELISA Kits
  • Functional ELISA Kits
  • Phospho-Specific ELISA Kits
  • Custom ELISA Kits
  • Proteins
  • All Proteins
  • Recombinant Proteins
  • Native Proteins
  • Over-expression Lysates
  • Cell and Tissue Lysates
  • Bio-active Proteins
  • Animal-free Proteins
  • Synthetic Peptides
  • Immunohistochemistry
  • Comprehensive IHC Reports
  • Custom IHC Services
  • TCR Screening Services
  • IHC-plus Antibodies
  • Other
  • Blocking Peptides
Services
  • Immunohistochemistry Services

  • Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

  • TCR Screening Services

  • Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Have a question? CustomerSupport@LSBio.com
Resources
  • Purchasing
  • Product Ordering Terms and Conditions
  • Holiday Schedule
  • About the LSBio Guarantee
  • About Our Rewards Program
  • Reference Material
  • About LSBio (LifeSpan BioSciences Inc.)
  • About Our 2-million Specimen Tissue Bank
  • About Our IHC Validation Process
  • About Our IHC-plus™ Immunohistochemistry Protocol
  • Publications
  • Secure Logins
  • Login to Our Secure FTP Site
  • Login to Our IHC Database
Distributors
Contact Us

LSBio
2401 Fourth Avenue Suite 900
Seattle WA 98121

Phone: 866-819-4732 (Toll Free North America)
206-374-1102 (International)

Fax: 866-206-6909 (Toll Free North America)
206-577-4565 (International)
How to Buy - Details about how to buy our products.

Orders@LSBio.com - To submit a new order.

Customer.Support@LSBio.com - To submit questions about existing orders, pricing, availability, bulk quotes, proforma invoice requests, or other billing issues.

Technical.Support@LSBio.com - To request technical information requests about an LSBio product or its application.

Sales@LSBio.com - To request information about fee-for-service contract IHC studies, IHC reports, distribution agreements, or general business development.

Worldwide Distributors List - To find your local distributor if you're not within the United States.
Quick Order ▾
View Cart

Anti-CD59 Antibody (FITC) LS-C5455

Ordering

Wt. Vol. Conc. Price
- 1000 µl - $495
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular CD59 Antibodies

Anti-CD59 Antibody (Biotin) LS-C35698
Mouse Monoclonal (IgG1) to Human CD59
Human
Flow Cytometry
Biotin Conjugated
Anti-CD59 Antibody (clone MEM-43/5) IHC-plus™ LS-B1853
Mouse Monoclonal [clone MEM-43/5] (IgG2b) to Human CD59
Human, Mouse
IHC - Paraffin, Western blot, Immunoprecipitation, Flow Cytometry
Unconjugated
Immunohistochemistry Image
Anti-CD59 Antibody (clone p282(H19)) IHC-plus™ LS-B1960
Mouse Monoclonal [clone p282(H19)] (IgG2a,k) to Human CD59
Human, Baboon, Monkey
IHC - Paraffin, Flow Cytometry
Unconjugated
Immunohistochemistry Image

100% Guaranteed 100% Guaranteed
Mouse Monoclonal (IgG1) to Human CD59
Human
Immunofluorescence, Flow Cytometry
FITC Conjugated

Details

Human CD59
Mouse
Human (tested or 100% immunogen sequence identity)
IgG1 Monoclonal
Fluorescein
Purified
Unmodified

Applications

  • Immunofluorescence (1:25)
  • Flow Cytometry

Specificity and Use

CD59 antibody was raised against human erythrocytes.
Binds to a 17-25kD glycoprotein, which is distributed on human cells and has a glycosyl-phosphatidylinositol (GPI) linkage to the plasma membrane. Cell reactivity: Recognizes all leucocytes, platelets, fibroblasts, erythrocytes and most cell lines. It is negative on U937 and Daudi cell lines. It is reduced on affected cells from patients with PNH with a distribution reflecting the clonal nature of the disease.
Studies of complement and homologous restriction of complement action of the properties of GPI linked proteins and in the characterization of cells from patients with PNH. Flow cytometry and indirect immunofluorescence: 1:25. Dilute with isotonic buffer. Use 50 ul of the appropriate dilution per 1x1E6 cells in 100 ul buffer. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

Packaging

PBS, pH 7.4, 0.2% BSA, 0.1% sodium azide.
Long term: Add glycerol (40-50%) -20°C; Short term: +4°C
For research use only.

About CD59

P13987 NM_000611 NP_000602.1

CD59 Antibody, 16.3A5 Antibody, 1F5 Antibody, 1F5 antigen Antibody, CD59 glycoprotein Antibody, EL32 Antibody, EJ16 Antibody, G344 Antibody, HRF-20 Antibody, MAC-IP Antibody, MACIF Antibody, Ly-6-like protein Antibody, MEM43 Antibody, MIRL Antibody, MEM43 antigen Antibody, MIN2 Antibody, MIN3 Antibody, MSK21 Antibody, p18-20 Antibody, Protectin Antibody, MAC-inhibitory protein Antibody, MIC11 Antibody, T cell-activating protein Antibody, CD59 antigen Antibody, EJ30 Antibody, HRF20 Antibody, Human leukocyte antigen MIC11 Antibody, Lymphocytic antigen CD59/MEM43 Antibody, MIN1 Antibody

CD59 is a cell surface glycoprotein that regulates complement-mediated cell lysis, and it is involved in lymphocyte signal transduction. This protein is a potent inhibitor of the complement membrane attack complex, whereby it binds complement C8 and/or C9 during the assembly of this complex, thereby inhibiting the incorporation of multiple copies of C9 into the complex, which is necessary for osmolytic pore formation.

Requested From: United States
Date Requested: 12/9/2016

Get Social With Us! Follow us on Facebook Follow us on Google+ Follow us on LinkedIn
Copyright © 2016 LifeSpan BioSciences, Inc. All Rights Reserved Privacy Policy
Catalog Number