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Anti-CD57 / HNK1 Antibody (clone HCD57) IHC-plus™ LS-B1948

Note: This antibody replaces LS-C41140

Ordering

Wt. Vol. Conc. Price
50 µg - 0.5 mg/ml $395
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular CD57 / HNK1 Antibodies

Anti-CD57 / HNK1 Antibody (PE, Cy5) LS-C13837
Mouse Monoclonal (IgM) to Human CD57 / HNK1
Human
IHC - Frozen, Immunoprecipitation, Flow Cytometry
PE, Cy5 Conjugated
Anti-CD57 / HNK1 Antibody (clone NK-1) IHC-plus™ LS-B7765
Mouse Monoclonal [clone NK-1] (IgM,k) to Human CD57 / HNK1
Human
IHC - Paraffin, Flow Cytometry
Unconjugated
Immunohistochemistry Image
Anti-CD57 / HNK1 Antibody LS-C180182
Rabbit Polyclonal to Human CD57 / HNK1
Human, Mouse
IHC - Paraffin, ICC
Unconjugated
Immunohistochemistry Image

100% Guaranteed 100% Guaranteed Publications Publications (2)
Mouse Monoclonal [clone HCD57] (IgM) to Human CD57 / HNK1
Human
IHC - Paraffin, Flow Cytometry
Unconjugated

Details

Human CD57 / HNK1
Mouse
Human (tested or 100% immunogen sequence identity)
IgM Monoclonal [HCD57]
Unconjugated
Affinity purified
Unmodified

Applications

  • IHC - Paraffin (10 µg/ml)
  • Flow Cytometry (1)

Specificity and Use

Immunohistochemistry: LS-B1948 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B1948 was determined to be 10 ug/ml.

Packaging

PBS, pH 7.2, 0.09% sodium azide.
Store undiluted at 4 degrees C
For research use only.

Publications (2)

1
T cell activation and senescence predict subclinical carotid artery disease in HIV-infected women. Kaplan RC, Sinclair E, Landay AL, Lurain N, Sharrett AR, Gange SJ, Xue X, Hunt P, Karim R, Kern DM, Hodis HN, Deeks SG. The Journal of infectious diseases. 2011 203:452-63. [PubMed:21220772] [PMC:PMC3071219]
2
Human NK cells proliferate and die in vivo more rapidly than T cells in healthy young and elderly adults. Lutz CT, Karapetyan A, Al-Attar A, Shelton BJ, Holt KJ, Tucker JH, Presnell SR. Journal of immunology (Baltimore, Md. : 1950). 2011 186:4590-8. [PubMed:21402893] [PMC:PMC3071442]

About CD57 / HNK1

Q9P2W7 NM_018644 NP_061114.2

B3GAT1 Antibody, CD57 Antibody, CD57 antigen Antibody, GlcAT-P Antibody, GLCUATP Antibody, Glucuronosyltransferase P Antibody, HNK-1 Antibody, HNK1 Antibody, LEU7 Antibody, GLCATP Antibody, NK-1 Antibody, NK1 Antibody, LEU7 antigen Antibody, GlcUAT-P Antibody

Involved in the biosynthesis of L2/HNK-1 carbohydrate epitope on glycoproteins. Can also play a role in glycosaminoglycan biosynthesis. Substrates include asialo-orosomucoid (ASOR), asialo-fetuin, and asialo-neural cell adhesion molecule. Requires sphingomyelin for activity: stearoyl-sphingomyelin was the most effective, followed by palmitoyl-sphingomyelin and lignoceroyl-sphingomyelin.

Immunohistochemistry

Immunohistochemistry
Anti-B3GAT1 / CD57 antibody IHC of human adrenal medulla. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B1948 concentration 10 ug/ml.

Flow Cytometry

Flow Cytometry
Human peripheral blood lymphocytes stained with purified HCD57, followed by anti-mouse IgGs FITC

Requested From: United States
Date Requested: 12/8/2016

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