Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse Monoclonal [clone MRC OX-45] (IgG1) to Rat CD48
Rat (tested or 100% immunogen sequence identity)
IgG1 Monoclonal [MRC OX-45]
Protein G purified
Flow Cytometry (0.5 µg/10E6 cells)
Specificity and Use
CD48 antibody was raised against rat T cell blasts (stimulated purified T helper cells with allogeneic irradiated rat spleen cells).
Anti-rat CD45 (Blast-1) monoclonal antibody recognizes a rat cell surface glycoprotein of 45 kD that is present on a wide variety of hematopoietic cells and on endothelial cells. The antigen is identical to the mouse BCM1 antigen. This antibody inhibits.
PBS, 0.02% sodium azide.
Store at 4°C for short term applications. For long term storage, aliquot and store at -20°C.
CD48 is a member of the CD2 subfamily of immunoglobulin-like receptors which includes SLAM (signaling lymphocyte activation molecules) proteins. The encoded protein is found on the surface of lymphocytes and other immune cells, dendritic cells and endothelial cells, and participates in activation and differentiation pathways in these cells.