Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse Monoclonal [clone MRC OX-1] (IgG1) to Rat CD45 / LCA
Rat CD45 / LCA
Rat (tested or 100% immunogen sequence identity)
IgG1 Monoclonal [MRC OX-1]
Protein G purified
Flow Cytometry (0.05 µg/10E6 cells)
Specificity and Use
CD45 / LCA antibody was raised against rat thymocyte membrane glycoproteins.
Purified anti-rat CD45 monoclonal antibody was raised against rat leukocyte common antigen and with this it was shown that the antigen existed in different forms on different lymphoid cell types. The thymocyte, T lymphocyte and B lymphocyte forms were fou.
PBS, 0.02% sodium azide.
Store at 4°C for short term applications. For long term storage, aliquot and store at -20°C.
CD45 is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus is classified as a receptor type PTP.