Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse Monoclonal [clone 1.11.32] (IgG1) to Sheep CD45 / LCA
Sheep, Bovine, Goat
IHC - Paraffin, IHC - Frozen, Immunoprecipitation, Flow Cytometry (applications tested for the base form of this product only)
Sheep CD45 / LCA
Sheep, Bovine, Goat (tested or 100% immunogen sequence identity)
IgG1 Monoclonal [1.11.32]
Protein G purified
IHC - Paraffin
IHC - Frozen
(applications tested for the base form of this product only)
Specificity and Use
CD45 / LCA antibody was raised against ovine efferent lymphatic duct lymphocytes.
Recognizes the ovine CD45 (Leucocyte common antigen), which is expressed on all ovine lymphocytes, macrophages and granulocytes. It immunoprecipitates CD45 molecules of 190kD, 210kD and 225kD from lymph node lysates.
PBS, 0.09% sodium azide
+4°C or -20°C, Avoid repeated freezing and thawing.
CD45 is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus is classified as a receptor type PTP.
Sheep granulocytes stained with Mouse anti-Sheep CD45 followed by Goat anti-Mouse IgG H+L:FITC. This image was taken for the base form of this product. Alternate forms, such as conjugated, azide-free, or ready-to-use, have not been tested.
Requested From: United States
Date Requested: 10/25/2016