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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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CD275 / B7‑H2 / ICOS Ligand Antibody (PE) LS‑C92661
Antibody
ICOS Ligand antibody LS-C92661 is a PE-conjugated mouse monoclonal antibody to human ICOS Ligand (CD275 / B7-H2). Validated for Flow.
Catalog
Size
Price
LS-C92661-100
100 tst (0.1 mg/ml)
Unavailable

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Peripheral Human Monocytes stained with Mouse anti Human CD275.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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Product Description

ICOS Ligand antibody LS-C92661 is a PE-conjugated mouse monoclonal antibody to human ICOS Ligand (CD275 / B7-H2). Validated for Flow.
About CD275 / B7-H2 / ICOS Ligand
Ligand for the T-cell-specific cell surface receptor ICOS. Acts as a costimulatory signal for T-cell proliferation and cytokine secretion; induces also B-cell proliferation and differentiation into plasma cells. Could play an important role in mediating local tissue responses to inflammatory conditions, as well as in modulating the secondary immune response by co-stimulating memory T-cell function. O75144 AF289028 AAG01176.1

ICOSLG Antibody, B7RP1 Antibody, B7 homolog 2 Antibody, B7 homologue 2 Antibody, B7-H2 Antibody, B7H2 Antibody, B7RP-1 Antibody, CD275 antigen Antibody, ICOS ligand Antibody, GL50 Antibody, ICOS-L Antibody, ICOSL Antibody, KIAA0653 Antibody, B7-like protein Gl50 Antibody, B7-related protein 1 Antibody, CD275 Antibody, LICOS Antibody


Specifications

Target
Human CD275 / B7-H2 / ICOS Ligand
Host
Mouse
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG1 Monoclonal
Conjugations
Phycoerythrin
Purification
Protein G purified
Modifications
Unmodified
Applications
  • Flow Cytometry
Immunogen
CD275 - L cells.
Specificity
Recognizes human CD275. Reported to partially block the interaction between CD275 and CD278.
Usage
Suitable for use in Flow cytometry. Flow cytometry: Use 10 ul of the suggested working dilution to label 1x1E6 cells in 100ul. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
Presentation
PBS, pH 7.4, 0.09% sodium azide, 1% BSA. Labeled, R-Phycoerythrin (PE). Reconstitute, 1 ml ddH2O
Reconstitution
100 tst Distilled Water.
Storage
Store lyophilized at 4°C. Once reconstituted, aliquot and store at 4°C. Avoid freeze/thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: 
Date Requested: 6/24/2018

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