Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse (tested or 100% immunogen sequence identity)
Ammonium sulfate precipitation
IHC - Frozen (1:25 - 1:50)
Specificity and Use
Cd209b antibody was raised against isolated C3H thymic stromal cells.
Recognizes mouse SIGN-R1, a C-type lectin that has been identified as a murine homologue of the human CD-SIGN related molecule, L-SIGN. Mouse SIGN-R1 is specifically expressed on marginal zone macrophages in the spleen, medullary and subcapsular sinus macrophages in the lymph nodes, and at lower levels on liver sinusoidal endothelial cells. SIGN-R1 has not been detected on murine dendritic cell populations. ER-TR9 blocks the uptake of neutral polysaccharides by macrophages.
Suitable for use in Flow Cytometry and Immunohistochemistry. Immunohistochemistry: Frozen 1:25-1:50.