Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse Monoclonal [clone UMCD2] (IgG2a,k) to Human CD2
Immunofluorescence, Flow Cytometry
Mouse Monoclonal (IgG1) to Sheep CD2
IHC - Frozen, Immunoprecipitation, Flow Cytometry
Sheep, Goat (tested or 100% immunogen sequence identity)
Protein G purified
IHC - Frozen
Flow Cytometry (1:100 - 1:200)
Specificity and Use
CD2 antibody was raised against sheep T cell blasts.
Recognizes. IL-5 is a regulatory cytokine that induces terminal differentiation of late-developing B-cells to immunoglobulin secreting cells. May be used to neutralize IL-5 bioactivity in a functional assay and.
Flow Cytometry: Use 10 ul of the suggested working dilution to label 10^6 cells in 100 ul. Method sheets are available on request.
0.09% sodium azide.
Long term: -20°C; Short term: +4°C; Avoid freeze-thaw cycles.
CD2 is a surface antigen of the human T-lymphocyte lineage that is expressed on all peripheral blood T cells (summarized by Sewell et al., 1986 [PubMed 3490670]). It is one of the earliest T-cell markers, being present on more than 95% of thymocytes; it is also found on some natural killer cells but not on B lymphocytes.