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Anti-CD1D Antibody (clone WTH2) LS-C188724

Catalog Size Price
LS-C188724-100 100 µg (0.5 mg/ml) Unavailable

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100% Guaranteed
Mouse Monoclonal [clone WTH2] (IgG2a) to Rat CD1D
Rat, Mouse
IHC, IHC - Frozen, Western blot, Immunoprecipitation, Flow Cytometry, ELISA, Functional Assay


Rat CD1D
Rat, Mouse (tested or 100% immunogen sequence identity)
IgG2a Monoclonal [WTH2]


  • IHC
  • IHC - Frozen
  • Western blot
  • Immunoprecipitation
  • Flow Cytometry (1:2000)
  • Functional Assay

Specificity and Use

CD1D antibody was raised against rat CD1d-transduced M12.4.1. C3 cells.
Recognizes rat CD1d, a glycoprotein expressed on cortical thymocytes, certain T-cell leukemias and various other antigen presenting cells. CD1d binds self and non-self glycolipids and presents them to T-cell receptors on natural killer cells. When activated, natural killer cells produce Th1 and Th2 cytokines. Clone WTH2 recognizes a different, non-overlapping epitope than clone WTH1 (, or ), and binds with high affinity to the mature CD1d heavy chain independently of beta-2-microglobulin. Clone WTH2 efficiently blocks rat and mouse invariant natural killer T cell (iNKT cell) response to a-GalCer (an antigen for iNKT cells), consistently blocks activation of mouse type II NKT cell hybridomas and has a slightly lower affinity to native CD1d than clone WTH1. In western blotting clone WTH2 reacts weakly with rat tissue and does not cross react with mouse tissue. It reacts strongly with both rat and mouse antigens in flow cytometry and cross reacts weakly with mouse tissue in IHC and immunoprecipitation.


PBS, 0.02% sodium azide
4°C or -20°C, Avoid freeze-thaw cycles.
For research use only.

About CD1D

P15813 NM_001766 NP_001757.1

CD1D Antibody, CD1D antigen, d polypeptide Antibody, R3 Antibody, R3G1 Antibody, CD1d antigen Antibody, CD1d molecule Antibody, Thymocyte antigen CD1D Antibody

CD1D is a divergent member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1.

Requested From: 
Date Requested: 5/20/2018

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