Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse Monoclonal [clone CB-T6] (IgG1) to Human CD1A
IHC - Frozen, ELISA
Human, Mouse (tested or 100% immunogen sequence identity)
IgG1 Monoclonal [CB-T6]
IHC - Frozen
Specificity and Use
CD1A antibody was raised against jurkat T-ALL cells. After three weeks the mouse was boosted and the splenocytes fused with myeloma cell line NS0. A positive hybridoma obtained after three limiting dilutions served as source for the hybridoma.
Reacts with human CD1a, a trans membrane glycoprotein of 49 kD which is non-covalently associated with beta-microglobulin. Crossreactive with mouse thymocytes.
Can be used for staining of frozen tissues and ELISA.
CD1A is a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1.