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Anti-CD14 Antibody (clone CC-G33, FITC) LS-C188366

Ordering

Wt. Vol. Conc. Price
100 µg - 0.1 mg/ml $425
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular CD14 Antibodies

Anti-CD14 Antibody (aa57-64, clone MEM-18, FITC) LS-C46346
Mouse Monoclonal [clone MEM-18] (IgG1) to Human CD14
Human, Primate
Flow Cytometry
FITC Conjugated
Anti-CD14 Antibody (aa71-84) IHC-plus™ LS-B3012
Goat Polyclonal to Human CD14
Human
IHC - Paraffin, Western blot, ELISA
Unconjugated
Immunohistochemistry Image

100% Guaranteed 100% Guaranteed
Mouse Monoclonal [clone CC-G33] (IgG1) to Bovine CD14
Bovine, Human, Sheep, Water buffalo
Immunofluorescence, Flow Cytometry (applications tested for the base form of this product only)
FITC Conjugated

Details

Bovine CD14
Mouse
Bovine, Human, Sheep, Water buffalo (tested or 100% immunogen sequence identity)
IgG1 Monoclonal [CC-G33]
Fluorescein. Also available Unconjugated.
Protein G purified
Unmodified

Applications

  • Immunofluorescence
  • Flow Cytometry
  • (applications tested for the base form of this product only)

Specificity and Use

CD14 antibody was raised against partially purified polypeptides isolated from bovine leucocyte cell surface membrane.
Recognizes bovine CD14, a GPI-anchored membrane glycoprotein and monocyte/macrophage differentiation antigen, belonging to the lipopolysaccharide receptor family, also expressed weakly on microglia and Langerhans cells. CD14 acts as a receptor for the potent bacterial endotoxin, lipopolysaccharide (LPS), facilitated by LPS-binding protein (LBP). The binding of LPS to CD14 results in cell activation and the release of cytokines and the inflammatory response, and has been shown to upregulate the cell surface expression of adhesion molecules. Clone CC-G33 cross-reacts with human CD14 expressed on transfected COS-7 cells, and also recognizes an epitope on ovine CD14.
The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

Packaging

PBS, 0.09% sodium azide, 1% BSA
Long term: -20°C; Short term: +4°C; Avoid freeze-thaw cycles. Protect from light.
For research use only.

About CD14

P08571 NM_000591 NP_000582.1

CD14 Antibody, CD14 molecule Antibody, CD14 antigen Antibody

In concert with LBP, binds to monomeric lipopolysaccharide and delivers it to the MD-2/TLR4 complex, thereby mediating the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Up-regulates cell surface molecules, including adhesion molecules.

Flow Cytometry

Flow Cytometry
Flow cytometry of bovine peripheral blood monocytes with Mouse anti-Bovine CD14. This image was taken for the unconjugated form of this product. Other forms have not been tested.
 

Requested From: United States
Date Requested: 12/9/2016

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