Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse Monoclonal [clone 2F4/11] (IgG1) to Pig CD11R3
IHC - Frozen, Western blot, Immunoprecipitation, Flow Cytometry (applications tested for the base form of this product only)
Pig (tested or 100% immunogen sequence identity)
IgG1 Monoclonal [2F4/11]
Also available conjugated with FITC.
Protein G purified
IHC - Frozen
Flow Cytometry (1:25 - 1:50)
(applications tested for the base form of this product only)
Specificity and Use
CD11R3 antibody was raised against porcine alveolar macrophages.
Recognizes porcine CD11R3, a 155kD cell surface marker which is a member of the alpha integrin family. CD11R3 has a similar expression pattern to the human CD11b marker, being expressed on granulocytes, monocytes and alveolar macrophages, but not on lymphocytes, eythrocytes or platelets. Clone 2F4/11 is reported to block phagocytosis of complement-opsonized zymosan particles by polymononuclear granulocytes and alveolar macrophages. Removal of sodium azide is recommended prior to use in functional assays -.
PBS, 0.09% sodium azide
+4°C or -20°C, Avoid repeated freezing and thawing.