Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Rat Monoclonal [clone YKIX490.6.4] (IgG2c) to Dog CD11 + CD18
Immunoprecipitation, Flow Cytometry (applications tested for the base form of this product only)
Dog CD11 + CD18
Dog (tested or 100% immunogen sequence identity)
IgG2c Monoclonal [YKIX490.6.4]
Also available conjugated with FITC.
Protein G purified
Flow Cytometry (1:50 - 1:100)
(applications tested for the base form of this product only)
IHC - Paraffin
IHC - Frozen
IHC - Resin
Specificity and Use
CD11 + CD18 antibody was raised against canine thymocytes.
Recognizes the canine leukocyte cell adhesion molecule (LeuCAM) composed of the 180kD CD11a chain complexed with the 95kD common beta chain CD18. The CD11a/CD18 complex is also known as LFA-1. Dependent cell mediated cytotoxic (ADCC) lysis and homotypic cell adhesion.
Flow Cytometry: Use 10 ul of the suggested working dilution to label 10^6 cells in 100 ul.
PBS, 0.09% sodium azide.
+4°C or -20°C, Avoid repeated freezing and thawing.