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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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CCR9 Antibody (N‑Terminus, clone 9B1) LS‑C188347
Antibody
CCR9 antibody LS-C188347 is an unconjugated rat monoclonal antibody to mouse CCR9. Validated for Flow.
Catalog
Size
Price
LS-C188347-100
100 µg (1 mg/ml)
Unavailable

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Product Description

CCR9 antibody LS-C188347 is an unconjugated rat monoclonal antibody to mouse CCR9. Validated for Flow.
About CCR9
CCR9 is a member of the beta chemokine receptor family. It is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptors are key regulators of the thymocytes migration and maturation in normal and inflammation conditions. The specific ligand of this receptor is CCL25. P51686 NM_006641 NP_006632.2

CCR9 Antibody, C-C CKR-9 Antibody, CC-CKR-9 Antibody, CCR-9 Antibody, CDw199 antigen Antibody, C-C chemokine receptor 9 Antibody, C-C chemokine receptor type 9 Antibody, Chemokine c-c motif receptor 9 Antibody, CDw199 Antibody, G protein-coupled receptor 28 Antibody, GPR-9-6 Antibody, G-protein coupled receptor 28 Antibody, GPR28 Antibody


Specifications

Target
Mouse CCR9
Host
Rat
Reactivity
Mouse (tested or 100% immunogen sequence identity)
Clonality
IgG2a Monoclonal [9B1]
Conjugations
Unconjugated. Also available conjugated with RPE.
Purification
Protein G purified
Modifications
Unmodified. Also available Low Endotoxin.
Applications
  • Flow Cytometry (1:25 - 1:200)
  • (applications tested for the base form of this product only)
Immunogen
CCR9 antibody was raised against 25 amino acids from the amino terminal of murine CCR9, coupled to KLH.
Epitope
N-Terminus
Specificity
Detects mouse chemokine receptor 9 (CCR9), also known as CDw199. CCR9 is a seven transmembrane protein which is a member of the beta chemokines receptor family. CCR9 is expressed in thymus and small intestine, and mediates the recruitment and development of thymocytes in response to CCL25; the only known ligand of CCR9. CCR9 is an alternative co-receptor with CD4 for HIV infection, and has been implicated in adult T cell leukaemia. Two alternatively spliced transcript variants have been described. Clone 9B1 blocks CCL25-induced Ca2+ release, attenuating inflammation in a murine model of chronic ileitis when given in early disease stages.
Presentation
PBS, 0.09% sodium azide
Storage
4°C or -20°C, Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: 
Date Requested: 6/25/2018

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