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Anti-CCNL1 / Cyclin L1 Antibody IHC-plus™ LS-B80

Note: This antibody replaces LS-C19081


Wt. Vol. Conc. Price
50 µg 50 µl 1 mg/ml $395
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)

Most Popular CCNL1 / Cyclin L1 Antibodies

Anti-CCNL1 / Cyclin L1 Antibody (aa32-81) LS-C31235
Rabbit Polyclonal (IgG) to Human CCNL1 / Cyclin L1
Human, Monkey, Mouse, Rat, Bovine, Guinea pig, Pig, Xenopus
Western blot
Western blot Image
Anti-CCNL1 / Cyclin L1 Antibody (aa105-154) LS-C151188
Rabbit Polyclonal to Rat CCNL1 / Cyclin L1
Rat, Human, Monkey, Mouse, Bat, Bovine, Dog, Guinea pig, Pig, Rabbit, Xenopus, Zebrafish
Western blot
Western blot Image
Anti-CCNL1 / Cyclin L1 Antibody (C-Terminus) LS-C353503
Rabbit Polyclonal to Human CCNL1 / Cyclin L1
Human, Mouse, Rat, Bovine, Dog, Pig
IHC - Paraffin, Western blot
Immunohistochemistry Image

100% Guaranteed 100% Guaranteed Publications Publications (1)
Rabbit Polyclonal to Human CCNL1 / Cyclin L1
Human, Mouse, Rat
IHC - Paraffin, Western blot, Immunoprecipitation, ELISA


Human CCNL1 / Cyclin L1
Human, Mouse, Rat (tested or 100% immunogen sequence identity)
Protein A purified


  • IHC - Paraffin (10 µg/ml)
  • Western blot (1:1000 - 1:5000)
  • Immunoprecipitation
  • ELISA (1:5000 - 1:20000)

Specificity and Use

Synthetic construct consisting of full length Human Cyclin L1b protein.
Immunohistochemistry: LS-B80 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B80 was determined to be 10 ug/ml.


+4°C or -20°C, Avoid repeated freezing and thawing.
For research use only.

Publications (1)

Role of CDK/cyclin complexes in transcription and RNA splicing. Loyer P, Trembley JH, Katona R, Kidd VJ, Lahti JM. Cellular signalling. 2005 17:1033-51. [PubMed:15935619]

About CCNL1 / Cyclin L1

Q9UK58 NM_020307 NP_064703.1

CCNL1 Antibody, ANIA6A Antibody, Ania-6a Antibody, BM-001 Antibody, Cyclin L ania-6a Antibody, Cyclin L gamma Antibody, Cyclin L1 Antibody, Cyclin-L Antibody, Cyclin-L1 Antibody, PRO1073 Antibody

Cyclin L (also referred to as CCNL) is encoded by two highly related genes Cyclin L1 and Cyclin L2 (CCNL1 and CCNL2, respectively). Cyclin L has been shown to associate with the PITSLRE kinase and is involved in pre-mRNA processing. Both Cyclin L gene products can be alternatively spliced to produce two isoforms (known as 1 and 2 or alpha and beta). Cyclin L2 is ubiquitous, expressed at much higher levels than Cyclin L1, and thus is likely the major partner for the CDK11p110 protein kinase.


Anti-CCNL1 / Cyclin L1 antibody IHC of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B80 concentration 10 ug/ml.

Western blot

Western blot
Western blot of Protein A Purified anti-Cyclin L1/L2 antibody shows detection of a band ~35 kDa corresponding to Cyclin L (arrowhead) present in mouse brain whole cell lysate (800 nm channel - green). Marker proteins appear red (700 nm channel) and were used for molecular weight comparisons. Approximately 35 ug of lysate was separated by 4-20% SDS-PAGE followed by transfer to nitrocellulose. After blocking the membrane was probed with the primary antibody diluted to 1:2,500 for 2h at room temperature followed by washes and reaction with a 1:10000 dilution of IRDye800 conjugated Gt-a-Rabbit IgG [H&L] MX (611-132-122) for 45 min at room temperature. IRDye800 fluorescence image was captured using the Odyssey Infrared Imaging System developed by LI-COR. IRDye is a trademark of LI-COR, Inc. Other detection systems will yield similar results.

Requested From: United States
Date Requested: 10/22/2016

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