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CCDC6 encodes a coiled-coil domain-containing protein. The encoded protein is ubiquitously expressed and may function as a tumor suppressor. A chromosomal rearrangement resulting in the expression of a fusion gene containing a portion of this gene and the intracellular kinase-encoding domain of the ret proto-oncogene is the cause of thyroid papillary carcinoma.
Gene Name: | coiled-coil domain containing 6 |
Synonyms: | CCDC6, D10S170, H4, Protein H4, TPC, TST1, PTC |
Target Sequences: | NM_005436 NP_005427.2 Q16204 |
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