Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
CBY1 Antibody, Arb1 Antibody, C22orf2 Antibody, Chibby Antibody, HS508I15A Antibody, PGEA1 Antibody, PIGEA-14 Antibody, Protein chibby homolog 1 Antibody, PIGEA14 Antibody, ARPP-binding protein Antibody, CBY Antibody, Chibby homolog 1 (Drosophila) Antibody, Coiled-coil protein PIGEA-14 Antibody, Cytosolic leucine-rich protein Antibody
Beta-catenin is a transcriptional activator and oncoprotein involved in the development of several cancers. The protein encoded by this gene interacts directly with the C-terminal region of beta-catenin, inhibiting oncogenic beta-catenin-mediated transcriptional activation by competing with transcription factors for binding to beta-catenin. Two transcript variants encoding different isoforms have been found for this gene.
Formalin-fixed and paraffin-embedded human brain tissue reacted with HRIHFB2025 Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Western blot of HRIHFB2025 Antibody in MDA-MB231 cell line lysates (35 ug/lane). HRIHFB2025 (arrow) was detected using the purified antibody.
HRIHFB2025 Antibody flow cytometry of MDA-MB231 cells (right histogram) compared to a negative control cell (left histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.