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Anti-CBX3 / HP1 Gamma Antibody (aa2-15) IHC-plus™ LS-B8717

Note: This antibody replaces LS-C152746, LS-C24210
Catalog Size Price
LS-B8717-50 50 µg Unavailable

Most Popular CBX3 / HP1 Gamma Antibodies

Anti-CBX3 / HP1 Gamma Antibody LS-C24209
Mouse Monoclonal (IgG1) to Mouse CBX3 / HP1 Gamma
Mouse, Human
IHC, Immunofluorescence, Western blot, ELISA
Unconjugated
Anti-CBX3 / HP1 Gamma Antibody (aa2-15) IHC-plus™ LS-B8717
Rabbit Polyclonal (IgG) to Mouse CBX3 / HP1 Gamma
Mouse, Human, Monkey, Rat, Bat, Bovine, Dog, Guinea pig, Horse, Pig
IHC - Paraffin, Western blot
Unconjugated
Immunohistochemistry Image
Anti-CBX3 / HP1 Gamma Antibody (aa75-125) IHC-plus™ LS-B12210
Rabbit Polyclonal (IgG) to Human CBX3 / HP1 Gamma
Human, Mouse, Rat, Bovine, Dog, Guinea pig, Horse, Rabbit
IHC - Paraffin, Immunofluorescence, Immunoprecipitation
Unconjugated
Immunohistochemistry - Paraffin Image
Anti-CBX3 / HP1 Gamma Antibody (C-Terminus) IHC-plus™ LS-B12401
Rabbit Polyclonal (IgG) to Human CBX3 / HP1 Gamma
Human, Mouse, Rat, Bovine, Dog, Chicken, Xenopus
IHC - Paraffin, Immunofluorescence
Unconjugated
Immunohistochemistry - Paraffin Image
Anti-CBX3 / HP1 Gamma Antibody LS-C394115
Mouse Monoclonal to Human CBX3 / HP1 Gamma
Human, Mouse
IHC - Paraffin, ICC, Western blot, Immunoprecipitation
Unconjugated
Immunohistochemistry Image

100% Guaranteed
Rabbit Polyclonal (IgG) to Mouse CBX3 / HP1 Gamma
Mouse, Human, Monkey, Rat, Bat, Bovine, Dog, Guinea pig, Horse, Pig
IHC - Paraffin, Western blot
Unconjugated

Details

Mouse CBX3 / HP1 Gamma
Rabbit
Mouse, Human, Monkey, Rat, Bat, Bovine, Dog, Guinea pig, Horse, Pig (tested or 100% immunogen sequence identity)
Chicken (at least 90% immunogen sequence identity)
IgG Polyclonal
Unconjugated
Protein A purified
Unmodified

Applications

  • IHC - Paraffin (5 µg/ml)
  • Western blot

Specificity and Use

Peptide corresponding to amino acids 2-15 (ASNKTTLQKMGKKQ) of mouse HP1 gamma protein Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Orangutan, Gibbon, Monkey, Marmoset, Mouse, Rat, Panda, Dog, Bovine, Bat, Horse, Pig, Opossum, Guinea pig (100%); Turkey, Zebra finch, Chicken, Platypus (93%).
aa2-15
HP1

Packaging

0.1 M Tris-glycine, pH 7.4, 0.15 M sodium chloride, 0.05% sodium azide, 30% glycerol
Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles.
For research use only.

About CBX3 / HP1 Gamma

Q13185 NM_016587 NP_057671.2

CBX3 Antibody, Chromobox homolog 3 Antibody, HP1Hs-gamma Antibody, Heterochromatin-like protein 1 Antibody, Modifier 2 protein Antibody, HP1-GAMMA Antibody, Chromobox protein homolog 3 Antibody, HECH Antibody, HP1 gamma Antibody, HP1 gamma homolog Antibody

Seems to be involved in transcriptional silencing in heterochromatin-like complexes. Recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. May contribute to the association of the heterochromatin with the inner nuclear membrane through its interaction with lamin B receptor (LBR). Involved in the formation of functional kinetochore through interaction with MIS12 complex proteins.

Immunohistochemistry

Immunohistochemistry
Anti-CBX3 / HP1 Gamma antibody IHC staining of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Western blot

Western blot
WB: HeLa nuclear extract was probed with Anti-HP1 Gamma.

Requested From: 
Date Requested: 12/18/2017

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