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Only known pyridoxal phosphate-dependent enzyme that contains heme. Important regulator of hydrogen sulfide, especially in the brain, utilizing cysteine instead of serine to catalyze the formation of hydrogen sulfide. Hydrogen sulfide is a gastratransmitter with signaling and cytoprotective effects such as acting as a neuromodulator in the brain to protect neurons against hypoxic injury.
Gene Name: | cystathionine-beta-synthase |
Synonyms: | CBS, Beta-thionase, Cystathionine beta-synthase, HIP4, Methylcysteine synthase, Serine sulfhydrase, Cystathionine-beta-synthase |
Target Sequences: | NM_000071 NP_000062.1 P35520 |
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