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Anti-CASP8AP2 / FLASH Antibody (C-Terminus) IHC-plus™ LS-B198

Note: This antibody replaces LS-C2667

Ordering

Wt. Vol. Conc. Price
50 µg - - $395
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular CASP8AP2 / FLASH Antibodies

Anti-CASP8AP2 / FLASH Antibody (N-Terminus) IHC-plus™ LS-B197
Rabbit Polyclonal
Human, Mouse
IHC - Paraffin, Western blot
Unconjugated
Immunohistochemistry Image
Anti-CASP8AP2 / FLASH Antibody (C-Terminus) IHC-plus™ LS-B198
Rabbit Polyclonal
Human
IHC - Paraffin, Western blot
Unconjugated
Immunohistochemistry Image
Anti-CASP8AP2 / FLASH Antibody (C-Terminus) IHC-plus™ LS-B206
Rabbit Polyclonal to Human CASP8AP2 / FLASH
Human
IHC - Paraffin, ICC, Western blot
Unconjugated
Immunohistochemistry Image

100% Guaranteed 100% Guaranteed
Rabbit Polyclonal
Human
IHC - Paraffin, Western blot
Unconjugated

Details

CASP8AP2 / FLASH
Rabbit
Human (tested or 100% immunogen sequence identity)
Polyclonal
Unconjugated
Purified IgG
Unmodified

Applications

  • IHC - Paraffin (10 µg/ml)
  • Western blot (1:500 - 1:1000)

Specificity and Use

CASP8AP2 / FLASH antibody was raised against c-terminus of the FLASH protein (proprietary peptide)
C-Terminus
Reacts with the C terminus of the FLASH protein.
Immunohistochemistry: LS-B198 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B198 was determined to be 10 ug/ml.

Packaging

PBS, 0.02% sodium azide.
+4°C or -20°C, Avoid repeated freezing and thawing.
For research use only.

About CASP8AP2 / FLASH

Q9UKL3 NM_012115 NP_036247.1

CASP8AP2 Antibody, CASP8 associated protein 2 Antibody, CASP8-associated protein 2 Antibody, CED-4 Antibody, FLICE associated huge Antibody, FLICE-associated huge protein Antibody, KIAA1315 Antibody, FLASH Antibody, FLASH homolog RIP25 Antibody, Human FLASH Antibody, RIP25 Antibody, Caspase 8 associated protein 2 Antibody

A novel mammalian CED-4 homologous was recently identified and cloned in mouse and human and designated FLASH (for FLICE-associated huge protein). FLASH is involved in Fas induced apoptosis. It is recruited to Fas after the receptor cross-linking. Overexpression of wild type of FLASH facilitates and its dominant negative form inhibits Fas induced apoptosis. FLASH interacts with the DEDs of caspase-8 and FADD through the DED-like domain of FLASH and mediates activation of caspase-8 (1).

Immunohistochemistry

Immunohistochemistry
Anti-CASP8AP2 / FLASH antibody IHC of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B198 concentration 10 ug/ml.
 

Requested From: United States
Date Requested: 12/11/2016

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