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Anti-Capicua / CIC Antibody (aa1500-1608) IHC-plus™ LS-B4752

Note: This antibody replaces LS-C33990

Ordering

Wt. Vol. Conc. Price
- 100 µl 1 mg/ml $395
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular Capicua / CIC Antibodies

Anti-Capicua / CIC Antibody (aa1500-1608) IHC-plus™ LS-B4752
Rabbit Polyclonal to Human Capicua / CIC
Human, Mouse, Rat, Dog
IHC - Paraffin, Western blot, Immunoprecipitation
Unconjugated
Immunohistochemistry Image
Anti-Capicua / CIC Antibody (aa1150-1200) IHC-plus™ LS-B5230
Rabbit Polyclonal to Human Capicua / CIC
Human, Mouse, Rat, Dog
IHC - Paraffin, Western blot, Immunoprecipitation
Unconjugated
Immunohistochemistry Image
Anti-Capicua / CIC Antibody (aa174-203) LS-C168780
Rabbit Polyclonal to Human Capicua / CIC
Human, Mouse
IHC - Paraffin, Western blot
Unconjugated
Immunohistochemistry Image

100% Guaranteed 100% Guaranteed Publications Publications (1)
Rabbit Polyclonal to Human Capicua / CIC
Human, Mouse, Rat, Dog
IHC - Paraffin, Western blot, Immunoprecipitation (applications tested for the base form of this product only)
Unconjugated

Details

Human Capicua / CIC
Rabbit
Human, Mouse, Rat, Dog (tested or 100% immunogen sequence identity)
Polyclonal
Unconjugated. Also available conjugated with Biotin, DY650, DY488, DY550.
Immunoaffinity purified
Unmodified

Applications

  • IHC - Paraffin (7.5 - 10 µg/ml)
  • Western blot (1:1000 - 1:2500)
  • Immunoprecipitation (2 - 5 µg/tst)
  • (applications tested for the base form of this product only)

Specificity and Use

Capicua / CIC antibody was raised against the epitope recognized by this antibody maps to a C-terminal region within residue 1500-1608 of human Capicua. [NCBI# NP_055940.3]
aa1500-1608
Recognizes an epitope mapping between amino acids 1500 and the C-terminus of human CIC.

Packaging

Tris-citrate/phosphate buffer, pH 7-8, 0.09% sodium azide.
Store at 4-8 degrees C. Do not freeze.
For research use only.

Publications (1)

1
Loss of CIC and FUBP1 expressions are potential markers of shorter time to recurrence in oligodendroglial tumors. Chan AK, Pang JC, Chung NY, Li KK, Poon WS, Chan DT, Shi Z, Chen L, Zhou L, Ng HK. Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc. Mar;27:332-42. [Full Text Article] [PubMed:24030748]

About Capicua / CIC

Q96RK0 NM_015125 NP_055940.3

CIC Antibody, Capicua homolog (Drosophila) Antibody, Capicua Antibody, Capicua (Drosophila) homolog Antibody, KIAA0306 Antibody, Protein capicua homolog Antibody

Capicua / CIC is an ortholog of the Drosophila melanogaster capicua gene, and is a member of the high mobility group (HMG)-box superfamily of transcriptional repressors. This protein contains a conserved HMG domain that is involved in DNA binding and nuclear localization, and a conserved C-terminus.

Immunohistochemistry

Immunohistochemistry
Anti-CIC antibody IHC of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4752 concentration 7.5 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Immunohistochemistry

Immunohistochemistry
Anti-CIC antibody IHC of human brain. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4752 concentration 7.5 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

Western blot
Detection of Human CIC/Capicua by Western Blot and Immunoprecipitation. Samples: 1 mg for IP, 20% of IP loaded and 293T (T; 50 mcg) cells. Antibodies: Affinity purified rabbit anti- CIC antibody used for WB at 1 mcg/ml (A and B) and used for IP at 3 mcg/mg lysate. CIC was also immunoprecipitated by rabbit anti-CIC antibody which recognizes an upstream epitope. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Immunoprecipitation

Immunoprecipitation
Immunoprecipitation of CIC from HeLa cell lysates using antibody LS-B4752. Lane 2 shows extracts immunoprecipitated with an IgG control antibody. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Requested From: United States
Date Requested: 12/5/2016

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