Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
CAMK2 / CAMKII antibody was raised against synthetic peptide aa281-291 (KMHRQE[pT]VDCLK) corresponding to rat calmodulin- dependent protein kinase II, subunit.
Recognizes phospho-CCaM Kinase II, alpha, beta subunits at Mr 50 and 60kD, respectively. Species cross-reactivity: Rat. Species sequence homology: mouse, rat b-11/12, Human, porcine, rat g-10/12, porcine, rat z-10/12. Predicted to cross-react with mouse, porcine, Xenopus and Drosophila.
Suitable for use in Western Blot. Western Blot: 0.5-2g/ml detect the phosphorylated alpha and beta subunits of CaM Kinase II in a rat brain microsomal preparation. Pretreating blots with 400U/ml of phosphatase prior to incubation with this lot of antibody abolished the detection of phospho-CaM Kinase II. Treatment with phosphatase had no effect on detection by a. non-phosphospecific antibody to CaM Kinase II.
0.1 M Tris-glycine, pH 7.4, 0.15 M sodium chloride, 0.05% sodium azide, 30% glycerol.
Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.