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CACNA2D4 is a member of the alpha-2/delta subunit family, a protein in the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Various versions of each of these subunits exist, either expressed from similar genes or the result of alternative splicing. Research on a highly similar protein in rabbit suggests the protein described in this record is cleaved into alpha-2 and delta subunits. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.
Gene Name: | calcium channel, voltage-dependent, alpha 2/delta subunit 4 |
Family/Subfamily: | Ion channel , Calcium channel - alpha subunit 2 / delta |
Synonyms: | CACNA2D4, RCD4 |
Target Sequences: | AF516695 AAN06672.1 Q7Z3S7 |
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