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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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CACNA2D1 Antibody (aa370‑383) LS‑C54598
CACNA2D1 antibody LS-C54598 is an unconjugated goat polyclonal antibody to human CACNA2D1. Validated for Peptide-ELISA and WB.
Catalog
Size
Price
LS-C54598-100
100 µg (0.5 mg/ml)
$405

Popular CACNA2D1 Products

Anti-CACNA2D1 antibody IHC of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B162 concentration 2.5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Human, Mouse, Rat, Bovine, Dog, Guinea pig, Horse, Pig, Rabbit
Applications: IHC, IHC - Paraffin, Western blot
Anti-CACNA2D1 antibody IHC of human nerve. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B6739 concentration 10 ug/ml.
Species: Human
Applications: IHC, IHC - Paraffin, Western blot
Antibody
Species: Human, Mouse, Rat
Applications: IHC, Western blot, ELISA
Western blot of CACNA2D1 Antibody in mouse brain tissue lysates (35 ug/lane). CACNA2D1 (arrow) was detected using the purified antibody.
Species: Human
Applications: Western blot, Flow Cytometry

Product Description

CACNA2D1 antibody LS-C54598 is an unconjugated goat polyclonal antibody to human CACNA2D1. Validated for Peptide-ELISA and WB.
About CACNA2D1
The preproprotein encoded by this gene is cleaved into multiple chains that comprise the alpha-2 and delta subunits of the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization. Mutations in this gene can cause cardiac deficiencies, including Brugada syndrome and short QT syndrome. Alternate splicing results in multiple transcript variants, some of which may lack the delta subunit portion. P54289 NM_000722 NP_000713.2

CACNA2D1 Antibody, Alpha2delta-1 Antibody, CCHL2A Antibody, CACNA2 Antibody, CACNL2A Antibody, DHSCCA Antibody, MHS3 Antibody, RB-alpha 2 Antibody, DHPR delta Antibody


Specifications

Target
Human CACNA2D1
Host
Goat
Reactivity
Human (tested or 100% immunogen sequence identity)
Predicted
Mouse, Rat, Bovine, Dog, Horse, Rabbit (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • Western blot (1:16000) & (0.03 - 0.1 µg/ml)
  • Peptide Enzyme-Linked Immunosorbent Assay (1:16000)
Failed Applications
  • IHC - Paraffin
Immunogen
CACNA2D1 antibody was raised against synthetic peptide C-QEIFNKYNKDKKVR from an internal region of human CACNA2D1 (NP_000713.2). Percent identity with other species by BLAST analysis: Human (100%), Gorilla (93%), Orangutan (93%), Gibbon (93%), Mouse (93%), Rat (93%), Elephant (93%), Panda (93%), Dog (93%), Bovine (93%), Horse (93%), Rabbit (93%), Opossum (93%), Bat (86%), Chicken (86%), Platypus (86%).
Blocking Peptide
LS-E26363 - Lyophilized - 100 µg - $145.00
Immunizing peptide used to generate LS-C54598. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
Epitope
aa370-383
Specificity
Human CACNA2D1.
Presentation
TBS, pH 7.3, 0.02% Sodium Azide, 0.5% BSA
Storage
Store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.

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Images

Western blot

Antibody (0.03 ug/ml) staining of Human Brain (Cerebellum) lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Antibody (0.03 ug/ml) staining of Human Brain (Cerebellum) lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Western blot

Antibody (0.03 ug/ml) staining of Human Brain (Cerebellum) lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Antibody (0.03 ug/ml) staining of Human Brain (Cerebellum) lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Western blot

Antibody (0.03 ug/ml) staining of Human Brain (Cerebellum) lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Antibody (0.03 ug/ml) staining of Human Brain (Cerebellum) lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Western blot

Antibody (0.03 ug/ml) staining of Human Brain (Cerebellum) lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Antibody (0.03 ug/ml) staining of Human Brain (Cerebellum) lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Requested From: United States
Date Requested: 9/19/2018

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