Human C1qRP / CD93

Mouse

Human (tested or 100% immunogen sequence identity)

Monoclonal

X-2

Biotin

Affinity purified

Unmodified

Human monocytes

The antigen has been assigned to the CDw93 cluster, the epitope has not been further characterized. Antigen distribution: Isolated cells: Positive with all granulocytes, with staining increasing transiently upon maturation. Antigen expression is increased by TNFa, GM-CSF, (fMLP) treatment. No effect on superoxide production by binding to neutrophils has been noted. PMA stimulation causes down regulation of the antigen. Positive with monocytes following fMLP, TNF, GM-CSF treatment. Antigen expression decreases on cultured monocytes. Positive on AML cases with monocytic component. Positive on cell lines HL-60, Namalva, K562, THP-1, U937, negative on HMC-1 (human mast cell line). Tissue sections: Monoclonal antibody X-2 stains epitheloid cells and Rosai-Dorfman cells and most endothelial cells in the synovial membrane of RA patients. Specificity: Human: granulocytes, monocytes, endothelial cells (main cellular reactivity). Other: not tested.

• IHC
• IHC - Frozen (1:400)

The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

Lyophilized from PBS pH 7.2, 10mg/ml BSA, 0.01% thimerosal

Reconstitute with 0.5ml distilled H2O.

Store at 4°C.

For research use only. Intended for use by laboratory professionals.

This antibody carries the LSBio 100% Guarantee.

Uniprot: Q9NPY3 NCBI: NM_012072 NP_036204.2