Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse Monoclonal [clone CLB-12.8] (IgG1) to Human c-ANCA
Human (tested or 100% immunogen sequence identity)
IgG1 Monoclonal [CLB-12.8]
Specificity and Use
c-ANCA antibody was raised against ascites fluid of tumor bearing BALB/c mice.
This MAB reacts with the human myeloid lysosomal serine protease (AKA 29kD c-ANCA-antigen) The AB does react with human cells of myeloid lineage, from early promyelocytes to neutrophils and monocytes. Also reacts with neutrophils and monocytes from chimpanzees.
20 mM Tris, 150 mM sodium chloride, pH 8.0, 10 mg/ml BSA, 0.1% sodium azide.
Store at 4°C. Product is photosensitive and should be protected from light.