Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Human, Mouse (tested or 100% immunogen sequence identity)
Specificity and Use
BRUNOL4 / CELF4 antibody was raised against recombinant fragment corresponding to a region within amino acids 1 and 172 of BRUNOL4 (SwissProt Q9BZC1). Percent identity by BLAST analysis: Human, Mouse (100%).
Human CELF4 / BRUNOL4
Antibody reactive against recombinant protein, detects immunogen. Further validation in progress.
0.1 M Tris-glycine, pH 7, 20% Glycerol, 0.01% Thimerosal
Aliquot and freeze at -20° C. Avoid freeze-thaw cycles.
CELF4 Antibody, BRUNOL-4 Antibody, Brunol5 Antibody, CELF-4 Antibody, Bruno-like protein 4 Antibody, CUG-BP and ETR-3 like factor 4 Antibody, LYST-interacting protein LIP9 Antibody, RNA-binding protein BRUNOL-4 Antibody, BRUNOL4 Antibody, RNA-binding protein BRUNOL4 Antibody
RNA-binding protein implicated in the regulation of pre-mRNA alternative splicing. Mediates exon inclusion and/or exclusion in pre-mRNA that are subject to tissue-specific and developmentally regulated alternative splicing. Specifically activates exon 5 inclusion of cardiac isoforms of TNNT2 during heart remodeling at the juvenile to adult transition. Promotes exclusion of both the smooth muscle (SM) and non-muscle (NM) exons in actinin pre-mRNAs. Activates the splicing of MAPT/Tau exon 10.