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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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Botulinum Neurotoxin Type A Antibody (C‑Terminus) LS‑C79415
Botulinum Neurotoxin Type A antibody LS-C79415 is an unconjugated mouse monoclonal antibody to clostridium botulinum Botulinum Neurotoxin Type A. Validated for ELISA, Func, IF and RIA.
Catalog
Size
Price
LS-C79415-1000
1000 µl
$485
Description
Botulinum Neurotoxin Type A antibody LS-C79415 is an unconjugated mouse monoclonal antibody to clostridium botulinum Botulinum Neurotoxin Type A. Validated for ELISA, Func, IF and RIA.
Target
Clostridium botulinum Botulinum Neurotoxin Type A
Host
Mouse
Reactivity
Clostridium botulinum (tested or 100% immunogen sequence identity)
Clonality
IgG2b,k Monoclonal
Conjugations
Unconjugated
Purification
Tissue culture supernatant
Modifications
Unmodified
Applications
  • Immunofluorescence
  • ELISA
  • Functional Assay
  • Radioimmunoassay
Immunogen
Synthetic peptide analog of the carboxyl terminal region of BoTox-A.
Epitope
C-Terminus
Specificity
Recognizes BoTox-A (1280-1292), and BoTox-A, but does not react with BoTox-B, BoTox-C, BoTox-E, or BoTox-F (1272-1280). Binds to intact whole BoTox-A by ELISA, RIA and cell staining techniques. Found to inhibit the binding of BoTox-A to Neuro2A cells treated with GT1b ganglioside prior to the addition of the toxin, and prior incubation of the antibody with the synthetic peptide immunogen has been shown to eliminate the inhibition of cellular binding by the antibody.
Usage
Suitable for use in ELISA, RIA, Immunofluorescence and Inhibition of BoTox-A binding to Neuro2A Cells. The staining pattern was observed using epifluorescent microscopy. Inhibition: Inhibits the binding of BoTox-A to Neuro2A cells treated with GT1b ganglioside prior to the addition of the toxin, and prior incubation of the antibody with the synthetic peptide. The immunogen has been shown to eliminate the inhibition of cellular binding by the antibody.
Presentation
Supplied as a liquid.
Storage
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
About Botulinum Neurotoxin Type A
P10845 P10845

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Requested From: United States
Date Requested: 12/9/2018
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