Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse Monoclonal [clone 8365M] (IgG) to Clostridium botulinum Botulinum Neurotoxin Type A
Immunofluorescence, ELISA, Radioimmunoassay
Clostridium botulinum Botulinum Neurotoxin Type A
Clostridium botulinum (tested or 100% immunogen sequence identity)
IgG Monoclonal [8365M]
Tissue culture supernatant
Specificity and Use
Botulinum Neurotoxin Type A antibody was raised against synthetic peptide analogue of the carboxyl terminal region of C. botulinum Toxin A.
Recognizes and binds to intact whole C. botulinum Toxin A, amino acids 1280-1292. Has been found to stain Neuro2A cells treated with GT1b ganglioside prior to the addition of C. botulinum Toxin A. Inhibits the entry of C. botulinum Toxin A to Neuro2A cells treated with GT1b ganglioside prior to the addition of the toxin. Cross-reactivity: C. botulinum Toxin A (1280-1292) and C. botulinum Toxin A: 100%, C. botulinum Toxin B, C, E and F (1272-1280): 0%.
Suitable for use in ELISA, Immunofluorescence and RIA. Immunocytochemistry1:50. Note: Prior incubation of the antibody with synthetic peptide immunogen has been shown to eliminate the inhibition of cellular binding by the antibody.
No preservatives added.
Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.