Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
BLK Antibody, Blk kinase Antibody, B lymphocyte kinase Antibody, B lymphoid tyrosine kinase Antibody, MODY11 Antibody, Protein kinase blk Antibody, Protein tyrosine kinase blk Antibody, B lymphoid kinase Antibody, p55-Blk Antibody, Tyrosine-protein kinase Blk Antibody
Non-receptor tyrosine kinase involved in B-lymphocyte development, differentiation and signaling. B-cell receptor (BCR) signaling requires a tight regulation of several protein tyrosine kinases and phosphatases, and associated coreceptors. Binding of antigen to the B-cell antigen receptor (BCR) triggers signaling that ultimately leads to B-cell activation.
Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
BLK Antibody (G1) western blot of HL-60 cell line lysates (35 ug/lane). The BLK antibody detected the BLK protein (arrow).
Western blot of anti-BLK antibody transiently transfected HEK-293 cell line lysate (1 ug/lane). BLK antibody(arrow) was detected using the purified antibody.
Western blot of anti-BLK antibody in mouse kidney tissue lysate. BLK (arrow) was detected using purified antibody. Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence.
Requested From: United States
Date Requested: 2/22/2017