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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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BIRC8 / ILP2 Antibody (aa2‑13) LS‑C42941
Note: This antibody replaces LS-C57068, LS-C24644
Antibody
ILP2 antibody LS-C42941 is an unconjugated rabbit polyclonal antibody to human ILP2 (BIRC8). Validated for WB.
Catalog
Size
Price
LS-C42941-100
100 µg (1 mg/ml)
Unavailable

Popular BIRC8 / ILP2 Products

Antibody
Species: Human
Applications: Western blot, ELISA
Anti-BIRC8 / ILP2 antibody IHC of human small intestine, Peyer's patch. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B457 concentration 5 ug/ml.
Species: Human, Mouse, Rat
Applications: IHC, IHC - Paraffin, ICC, Western blot
Western blot. All lanes: Baculoviral IAP repeat-containing protein 8 antibody at 6 ug/ml+mouse brain tissue. Secondary antibody: Goat polyclonal to rabbit at 1:10000 dilution. Predicted band size: 27 kDa. Observed band size: 27 kDa.
Species: Human, Mouse
Applications: Western blot, ELISA
Antibody
Species: Human
Applications: IHC, Western blot
Antibody
Species: Human
Applications: Western blot, ELISA

Product Description

ILP2 antibody LS-C42941 is an unconjugated rabbit polyclonal antibody to human ILP2 (BIRC8). Validated for WB.
About BIRC8 / ILP2
Apoptosis, or programmed cell death, is related to many diseases, such as cancer. Apoptosis is triggered by a variety of stimuli including members in the TNF family and prevented by the inhibitor of apoptosis (IAP) proteins. IAP proteins form a conserved gene family including IAP, XIAP/ILP-1/MIHA, and Livin/KIAP that bind to and inhibits specific proteases. A novel member in the IAP protein family was recently identified and designated ILP-2 for IAP-like protein-2. Q96P09 NM_033341 NP_203127.3

BIRC8 Antibody, HILP2 Antibody, ILP-2 Antibody, ILP2 Antibody, IAP-like protein 2 Antibody


Specifications

Target
Human BIRC8 / ILP2
Host
Rabbit
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Purification
Purified
Modifications
Unmodified
Applications
  • Western blot (1 - 2 µg/ml)
Immunogen
BIRC8 / ILP2 antibody was raised against synthetic peptide TGYEARLITFGT corresponding to amino acids 2-13 of human ILP-2. Percent identity by BLAST analysis: Human, Chimpanzee (100%); Gorilla (92%).
Epitope
aa2-13
Specificity
Recognizes Baculoviral IAP repeat-containing protein 8 also known as inhibitor of apoptosis protein- like protein 2, ILP-2 or BIRC8. ILP-2 is a 236 amino acid ~27 kD cytoplasmic protein belonging to the IAP family of apoptosis inhibitors and is expressed solely in the testis in normal tissue. ILP-2 is reported to bind to caspase 9 and is thought to protect against apoptosis mediated by BAX.
Usage
Western Blot: LS-C42941 detects a band of approximately 33kD in HepG2 and MOLT4°Cell lysates.
Presentation
PBS, 0.02% sodium azide.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: 
Date Requested: 6/23/2018

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