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Anti-BHLHB2 / DEC1 Antibody (C-Terminus, DY488) LS-C142760

Ordering

Wt. Vol. Conc. Price
- 100 µl - $365
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular BHLHB2 / DEC1 Antibodies

Anti-BHLHB2 / DEC1 Antibody (aa249-298) LS-C30309
Rabbit Polyclonal (IgG) to Human BHLHB2 / DEC1
Human, Monkey, Mouse, Rat, Guinea pig, Hamster, Horse, Pig
Western blot
Unconjugated
Western blot Image
Anti-BHLHB2 / DEC1 Antibody (C-Terminus) IHC-plus™ LS-B2222
Rabbit Polyclonal to Human BHLHB2 / DEC1
Human
IHC - Paraffin, Western blot, Immunoprecipitation
Unconjugated
Immunohistochemistry Image

100% Guaranteed 100% Guaranteed
Rabbit Polyclonal to Human BHLHB2 / DEC1
Human
IHC - Paraffin, Western blot, Immunoprecipitation (applications tested for the base form of this product only)
DY488 Conjugated

Details

Human BHLHB2 / DEC1
Rabbit
Human (tested or 100% immunogen sequence identity)
Polyclonal
DyLight 488. Also available Unconjugated or conjugated with Biotin, DY650, DY550.
Immunoaffinity purified
Unmodified

Applications

  • IHC - Paraffin
  • Western blot (1:5000 - 1:15000)
  • Immunoprecipitation (1:5000 - 1:15000)
  • (applications tested for the base form of this product only)

Specificity and Use

BHLHB2 / DEC1 antibody was raised against the epitope recognized by this antibody maps to a region between residues 350 and the C-terminus (residue 412) of human Differentially Expressed in Chondrocytes using the numbering given in entry NP_003661.1 (GeneID 8553)
C-Terminus
The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

Packaging

50 mM sodium borate
Store at 4°C. Do not freeze.
For research use only.

About BHLHB2 / DEC1

O14503 NM_003670 NP_003661.1

BHLHE40 Antibody, BHLHB2 Antibody, HLHB2 Antibody, SHARP2 Antibody, Stra14 Antibody, SHARP-2 Antibody

Transcriptional repressor involved in the regulation of the circadian rhythm by negatively regulating the activity of the clock genes and clock-controlled genes. Acts as the negative limb of a novel autoregulatory feedback loop (DEC loop) which differs from the one formed by the PER and CRY transcriptional repressors (PER/CRY loop). Both these loops are interlocked as it represses the expression of PER1/2 and in turn is repressed by PER1/2 and CRY1/2.

Immunohistochemistry

Immunohistochemistry
Anti-BHLHE40 antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2222 concentration 5 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

Western blot
Detection of Human DEC1 by Western Blot and Immunoprecipitation. Samples: Whole cell lysate from HeLa (50 mcg for WB) and 293T (1 mg/IP, 20% of IP loaded) cells. Antibodies: Affinity purified rabbit anti-DEC1 antibody used for WB at 0.1 mcg/ml (A) and 1 mcg/ml (B) and for IP at 3 mcg/mg lysate. DEC1 was also immunoprecipitated using 2 other rabbit anti-DEC1 antibodies, which recognize upstream epitopes. Detection: Chemiluminescence with exposure times of 3 minutes (A) and 30 seconds (B). This image was taken for the unconjugated form of this product. Other forms have not been tested.

Requested From: United States
Date Requested: 12/6/2016

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