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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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BCL3 / BCL‑3 Antibody (Internal) LS‑C4131
Antibody
BCL-3 antibody LS-C4131 is an unconjugated rabbit polyclonal antibody to human BCL-3 (BCL3). Validated for IP and WB.
Catalog
Size
Price
LS-C4131-200
200 µl (0.12 mg/ml)
Unavailable

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Product Description

BCL-3 antibody LS-C4131 is an unconjugated rabbit polyclonal antibody to human BCL-3 (BCL3). Validated for IP and WB.
About BCL3 / BCL-3
BCL3 / BCL-3 is a proto-oncogene candidate. It is identified by its translocation into the immunoglobulin alpha-locus in some cases of B-cell leukemia. The protein encoded by this gene contains seven ankyrin repeats, which are most closely related to those found in I kappa B proteins. This protein functions as a transcriptional co-activator that activates through its association with NF-kappa B homodimers. P20749 NM_005178 NP_005169.2

BCL3 Antibody, B-cell CLL/lymphoma 3 Antibody, B-cell leukemia/lymphoma 3 Antibody, B-cell lymphoma 3 protein Antibody, BCL-3 Antibody, BCL4 Antibody, D19S37 Antibody, Proto-oncogene BCL3 Antibody


Specifications

Target
Human BCL3 / BCL-3
Host
Rabbit
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • Western blot (2 - 6 µg/ml)
  • Immunoprecipitation
Immunogen
BCL3 / BCL-3 antibody was raised against synthetic peptide derived from the middle region of human BCL-3.
Epitope
Internal
Specificity
Reacts with the ~60kD human BCL-3 protein. Faint, non-specific bands may also be observed at ~30 and 36kD. Reactivity has been confirmed in Western blotting with REH human acute lymphocytic leukemia (ALL) (non-T, non-B), Nalm-6 human Pre-B peripheral blood leukemia, and Jurkat T lymphocyte leukemia lysates. This antibody also immunoprecipitated the BCL-3 protein from REH human acute lymphocytic leukemia lysates.
Usage
Suitable for use in Western Blot and Immunoprecipitation. Western Blot: 2-6 ug/ml. Immunoprecipitation: 14-20 ug/IP reaction.
Presentation
PBS, pH 7.4, 0.1% sodium azide, 40% glycerol.
Storage
Short term: 4°C; Long term: Add glycerol (40-50%) -20°C.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: 
Date Requested: 6/19/2018

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