Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
BAX, BCL2-associated X protein, Bcl2-L-4, Apoptosis regulator BAX, Bcl-2-like protein 4, BCL2L4
(tested or 100% immunogen sequence identity)
IHC - Paraffin
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
BAX antibody was raised against synthetic peptide corresponding to amino acids 43-61 of human Bax.
Recognizes the human Bax protein, a proapoptotic member of the Bcl-2 family. Bax migrates as a 21kD band when detected by the antibody in immunoblotting applications. Species cross-reactivity: Does not react with mouse.
Suitable for use in Western Blot, Immunohistochemistry and Immunoprecipitation. Immunohistochemistry (Paraffin sections): 1:1000-1:2000; Requires antigen retrieval using heat treatment prior to staining of paraffin sections. Immunoprecipitation: 1:1000. Positive control: Normal Breast Tissue (IHC).
Apoptosis plays a major role in normal organism development, tissue homeostasis, and removal of damaged cells. Disruption of this process has been implicated in a variety of diseases such as cancer. The Bcl-2 family of proteins is comprised of critical regulators of apoptosis that can be divided into two classes: those that inhibit apoptosis and those that promote cell death.