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Anti-Basigin / Emmprin / CD147 Antibody (clone MEM-M6/1, APC) LS-C57534

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Wt. Vol. Conc. Price
- 100 tst - $370
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Most Popular Basigin / Emmprin / CD147 Antibodies

Anti-Basigin / Emmprin / CD147 Antibody (N-Terminus, clone MEM-M6/1) IHC-plus™ LS-B3167
Mouse Monoclonal [clone MEM-M6/1] (IgG1) to Human Basigin / Emmprin / CD147
Human
IHC - Paraffin, Western blot, Immunoprecipitation, Flow Cytometry
Unconjugated
Immunohistochemistry Image
Anti-Basigin / Emmprin / CD147 Antibody (clone MEM-M6/1) IHC-plus™ LS-B1861
Mouse Monoclonal [clone MEM-M6/1] (IgG1) to Human Basigin / Emmprin / CD147
Human
IHC - Paraffin, Western blot, Immunoprecipitation, Flow Cytometry
Unconjugated
Immunohistochemistry Image

100% Guaranteed 100% Guaranteed
Mouse Monoclonal [clone MEM-M6/1] (IgG1) to Human Basigin / Emmprin / CD147
Human
Flow Cytometry
APC Conjugated

Details

Human Basigin / Emmprin / CD147
Mouse
Human (tested or 100% immunogen sequence identity)
IgG1 Monoclonal [MEM-M6/1]
Allophycocyanin
Affinity purified
Unmodified

Applications

Flow Cytometry (1:1)

Specificity and Use

Recognizes the human CD147 cell surface antigen, also known as Basigin, EMMPRIN and collagenase stimulatory factor. CD147 is a 385 amino acid single pass type 1 trans-membrane glycoprotein bearing 3 potential N-glycosylation sites, a single N-terminal (distal) and a more proximal in its extracellular region. Was raised and screened against recombinant extracellular region of huCD147 expressed in CHO cells, along with a number of other MEM-M6 clones. Epitope mapping indicates that clone MEM-M6/1 binds to an epitope within the distal Ig-like C-2 type domain. This is confirmed by flow cytometric studies using beads coated with constructs containing only the distal Ig-like or proximal Ig-like domains. Binds to both un-stimulated and phytohemagglutinin (PHA) stimulated (activated) T lymphocytes with levels of CD147 enhanced following PHA stimulation. CD147 is also expressed by peripheral blood and endothelial cells as well as many cultured cells of hematopoietic and non-hematopoietic origin.
Flow Cytometry: Use 10 ul of the suggested working dilution to label 10^6 cells or 100 ul whole blood. Method sheets are available on request. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

Packaging

Lyophilized, PBS, pH 7.4, 0.09% sodium azide, 1% BSA.
100 tst Distilled Water.
+4°C, avoid freezing
For research use only.

About Basigin / Emmprin / CD147

P35613 NM_001728 NP_001719.2

BSG Antibody, 5F7 Antibody, Basigin Antibody, Basigin (Ok blood group) Antibody, CD147 antigen Antibody, Collagenase stimulatory factor Antibody, EMMPRIN Antibody, OK Antibody, OK blood group antigen Antibody, TCSF Antibody, CD147 Antibody, M6 Antibody

Plays an important role in targeting the monocarboxylate transporters SLC16A1, SLC16A3 and SLC16A8 to the plasma membrane. Plays pivotal roles in spermatogenesis, embryo implantation, neural network formation and tumor progression. Stimulates adjacent fibroblasts to produce matrix metalloproteinases (MMPS). Seems to be a receptor for oligomannosidic glycans. In vitro, promotes outgrowth of astrocytic processes.

Flow Cytometry

Flow Cytometry
Human red blood cells stained with Mouse anti Human CD147: APC. This image was taken for the unconjugated form of this product. Other forms have not been tested.
 

Requested From: United States
Date Requested: 12/10/2016

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