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Anti-ATR Antibody LS-C83013

Catalog	Size	Price
LS-C83013-100	100 µg	Unavailable

Related Products

54 ATR Antibodies

Most Popular ATR Antibodies

Anti-ATR Antibody (aa2122-2380) LS-C42753

Antibody:	Rabbit Polyclonal (IgG) to Human ATR
Reactivity:	Human, Mouse, Bovine, Hamster
Application:	Western blot, Immunoprecipitation
Format:	Unconjugated

Anti-ATR Antibody (clone 1E9) IHC-plus™ LS-B4288

Antibody:	Mouse Monoclonal [clone 1E9] (IgG1,k) to Human ATR
Reactivity:	Human
Application:	IHC - Paraffin, ELISA
Format:	Unconjugated

Anti-ATR Antibody (aa394-443) LS-C118345

Antibody:	Rabbit Polyclonal (IgG) to Human ATR
Reactivity:	Human
Application:	IHC - Paraffin, ELISA
Format:	Unconjugated

Anti-ATR Antibody (aa400-460) LS-C355586

Antibody:	Rabbit Polyclonal (IgG) to Human ATR
Reactivity:	Human
Application:	Immunofluorescence, Western blot, Immunoprecipitation
Format:	Unconjugated

Anti-ATR Antibody (aa370-450) LS-C382213

Antibody:	Rabbit Polyclonal (IgG) to Human ATR
Reactivity:	Human
Application:	IHC, Western blot, ELISA
Format:	Unconjugated

Antibody:	Rabbit Polyclonal to Human ATR
Reactivity:	Human, Mouse
Application:	Western blot
Format:	Unconjugated

Details

Target:	Human ATR
Host:	Rabbit
Reactivity:	Human, Mouse (tested or 100% immunogen sequence identity)
Clonality:	Polyclonal
Conjugations:	Unconjugated
Modifications:	Unmodified

Applications

Approved:

Western blot (0.03 - 0.07 µg/ml)

Specificity and Use

Immunogen:	ATR antibody was raised against synthetic peptide representing a portion of the protein encoded within exon 29 (LocusLink ID 545).
Specificity:	Reacts with human and mouse. Antibody is affinity purified.

Packaging

Presentation:	Tris-citrate/phosphate, pH 7-8, 0.1% sodium azide
Storage:	Store at 2-8°C for up to 1 year. Avoid repeated freeze-thaw cycles.
Restrictions:	For research use only.

About ATR

Uniprot: Q13535 NCBI: NM_001184 NP_001175.2

Synonyms: ATR Antibody, FRAP-related protein-1 Antibody, FCTCS Antibody, SCKL1 Antibody, MEC1 Antibody, Protein kinase ATR Antibody, Rad3 related protein Antibody, SCKL Antibody, FRAP-related protein 1 Antibody, FRP1 Antibody

Description: Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]-Q. Phosphorylates BRCA1, CHEK1, MCM2, RAD17, RPA2, SMC1 and p53/TP53, which collectively inhibit DNA replication and mitosis and promote DNA repair, recombination and apoptosis.

(More About ATR)

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Date Requested: 6/25/2017

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