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ATR Antibody LS‑C83013
ATR antibody LS-C83013 is an unconjugated rabbit polyclonal antibody to ATR from human and mouse. Validated for WB.
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Species:
Human, Mouse, Bovine, Hamster
Applications:
Western blot, Immunoprecipitation
Species:
Human
Applications:
IHC, IHC - Paraffin, Peptide Enzyme-Linked Immunosorbent Assay
Species:
Human
Applications:
Immunofluorescence, Western blot, Immunoprecipitation
Product Description
ATR antibody LS-C83013 is an unconjugated rabbit polyclonal antibody to ATR from human and mouse. Validated for WB.
About ATR
Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]-Q. Phosphorylates BRCA1, CHEK1, MCM2, RAD17, RPA2, SMC1 and p53/TP53, which collectively inhibit DNA replication and mitosis and promote DNA repair, recombination and apoptosis.
Q13535
NM_001184
NP_001175.2
ATR Antibody, FRAP-related protein-1 Antibody, FCTCS Antibody, SCKL1 Antibody, MEC1 Antibody, Protein kinase ATR Antibody, Rad3 related protein Antibody, SCKL Antibody, FRAP-related protein 1 Antibody, FRP1 Antibody
Specifications
Target
Human ATR
Host
Rabbit
Reactivity
Human, Mouse
(tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Modifications
Unmodified
Applications
- Western blot (0.03 - 0.07 µg/ml)
Immunogen
ATR antibody was raised against synthetic peptide representing a portion of the protein encoded within exon 29 (LocusLink ID 545).
Specificity
Reacts with human and mouse. Antibody is affinity purified.
Presentation
Tris-citrate/phosphate, pH 7-8, 0.1% sodium azide
Storage
Store at 2-8°C for up to 1 year. Avoid repeated freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.
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Requested From:
Date Requested: 6/20/2018
Date Requested: 6/20/2018
