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Anti-ASIP Antibody (aa1-40) LS-C183744

Ordering

Wt. Vol. Conc. Price
- 50 µl - $680
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

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Anti-ASIP Antibody (aa1-40) LS-C183744
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100% Guaranteed 100% Guaranteed
Rabbit Polyclonal (IgG) to Human ASIP
Human
IHC, ICC
Unconjugated

Details

Human ASIP
Rabbit
Human (tested or 100% immunogen sequence identity)
IgG Polyclonal
Unconjugated
Antiserum
Unmodified

Applications

  • IHC
  • ICC (1:200)

Specificity and Use

ASIP antibody was raised against synthetic peptide corresponding aa1-40 of human Agouti.
aa1-40
Human Agouti. Sequence homology (0%): Orexin A (human, mouse, rat), human Orexin B, a-MSH, MCH (human, mouse, rat), NPY (human, rat), human Agouti-Related Protein (83-132)-NH2.

Packaging

Lyophilized
50 µl Sterile distilled water
Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C.
For research use only.

About ASIP

P42127 NM_001672 NP_001663.2

ASIP Antibody, Agouti-signaling protein Antibody, AGTIL Antibody, Agouti signaling protein Antibody, AGTI Antibody, Agouti switch protein Antibody, AGSW Antibody, SHEP9 Antibody, ASP Antibody, Nonagouti homolog Antibody

Involved in the regulation of melanogenesis. The binding of ASP to MC1R precludes alpha-MSH initiated signaling and thus blocks production of cAMP, leading to a down-regulation of eumelanogenesis (brown/black pigment) and thus increasing synthesis of pheomelanin (yellow/red pigment). In higher primates, agouti may affect the quality of hair pigmentation rather than its pattern of deposition. Could well play a role in neuroendocrine aspects of melanocortin action.

Requested From: United States
Date Requested: 12/10/2016

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