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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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ASIC1 / ACCN2 Antibody (N‑Terminus) LS‑C11720
ACCN2 antibody LS-C11720 is an unconjugated rabbit polyclonal antibody to ACCN2 (ASIC1) from human and rat. Validated for ELISA and WB.
Antibody
Catalog
Size
Price
LS-C11720-100
100 µg
$755

Popular ASIC1 / ACCN2 Products

Antibody
Species: Rat, Human, Mouse
Applications: IHC, Western blot
ACCN2 antibody LS-C110017 Western blot of HT1080 cell lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Human, Monkey, Mouse, Rat, Bat, Guinea pig, Horse, Pig, Rabbit, Chicken
Applications: Western blot
Antibody
Species: Human
Applications: IHC, IHC - Paraffin, Western blot, ELISA
Formalin-fixed and paraffin-embedded human brain tissue reacted with ACCN2 Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Species: Human
Applications: IHC, IHC - Paraffin, Western blot, Flow Cytometry
Antibody
Species: Mouse, Rat
Applications: IHC, ICC, Western blot

Product Description

ACCN2 antibody LS-C11720 is an unconjugated rabbit polyclonal antibody to ACCN2 (ASIC1) from human and rat. Validated for ELISA and WB.
About ASIC1 / ACCN2
Isoform 2 and isoform 3 function as proton-gated sodium channels; they are activated by a drop of the extracellular pH and then become rapidly desensitized. The channel generates a biphasic current with a fast inactivating and a slow sustained phase. Has high selectivity for sodium ions and can also transport lithium ions with high efficiency. Isoform 2 can also transport potassium, but with lower efficiency. It is nearly impermeable to the larger rubidium and cesium ions. P78348 NM_020039 NP_064423.2

ASIC1 Antibody, Acid-sensing ion channel 1 Antibody, ACCN2 Antibody, Acid-sensing ion channel Antibody, ASIC1A Antibody, BNaC2 Antibody, Brain sodium channel 2 Antibody, HBNaC2 Antibody, ASIC Antibody, ASIC1B Antibody


Specifications

Target
Rat ASIC1 / ACCN2
Host
Rabbit
Reactivity
Rat, Human (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • Western blot (1 - 10 µg/ml)
  • ELISA (0.5 - 1 µg/ml)
Immunogen
ASIC1 / ACCN2 antibody was raised against synthetic peptide sequence 20aa sequence near the extracellular, N-terminus, of rat ASIC1 (KLH coupled).
Epitope
N-Terminus
Specificity
Recognizes Acid Sensitive Ion Channel 1. No significant sequence homology is detected with other ASIC-beta or other ASICs. Species sequence Homology: Human: 100%.
Usage
Suitable for use in ELISA, Western Blot. Western Blot: 1-10 ug/ml (ECL). ELISA: 0.5-1 ug/ml using 5-10 ug control peptide/ug.
Presentation
100 mM Tris, pH 7.5, 0.05% Sodium Azide, 40% Glycerol, 0.2% BSA
Storage
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: United States
Date Requested: 8/16/2018

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