Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse (tested or 100% immunogen sequence identity)
Protein A purified
Western blot (2 - 3 µg/ml)
Specificity and Use
ASAP1 antibody was raised against amino acids 962-978 (VELAPKPQVGELPPKPG)of mouse ASAP1 were used as the immunogen. Percent identity with other species by BLAST analysis: Mouse (100%), Rat (88%), Human (82%), Gorilla (82%), Gibbon (82%), Monkey (82%), Marmoset (82%), Dog (82%), Bat (82%), Hamster (82%), Elephant (82%), Panda (82%), Horse (82%), Pig (82%).
PBS, 0.05% BSA, 0.05% sodium azide
Store at 4°C for short term applications. For long term storage, aliquot and store at -20°C.
Possesses phosphatidylinositol 4,5-bisphosphate-dependent GTPase-activating protein activity for ARF1 (ADP ribosylation factor 1) and ARF5 and a lesser activity towards ARF6. May coordinate membrane trafficking with cell growth or actin cytoskeleton remodeling by binding to both SRC and PIP2. May function as a signal transduction protein involved in the differentiation of fibroblasts into adipocytes and possibly other cell types (By similarity). Plays a role in ciliogenesis.
Western blot of ASAP1 in mouse brain lysate in the 1) absence and 2) presence of immunizing peptide using LS-C148543 at 2.0 ug/ml. Goat anti-rabbit Ig HRP secondary antibody, and PicoTect ECL substrate solution, were used for this test.
Requested From: United States
Date Requested: 2/26/2017